• Publications
  • Influence
Meta-analysis of Genome-wide Association Studies of Asthma In Ethnically Diverse North American Populations
Asthma is a common disease with a complex risk architecture including both genetic and environmental factors. We performed a meta-analysis of North American genome-wide association studies of asthmaExpand
  • 633
  • 10
CYP3A4-V and prostate cancer in African Americans: causal or confounding association because of population stratification?
Abstract.CYP3A4-V, an A to G promoter variant associated with prostate cancer in African Americans, exhibits large differences in allele frequency between populations. Given that the African AmericanExpand
  • 156
  • 10
Assembly of a pan-genome from deep sequencing of 910 humans of African descent
We used a deeply sequenced dataset of 910 individuals, all of African descent, to construct a set of DNA sequences that is present in these individuals but missing from the reference human genome. WeExpand
  • 99
  • 7
Prevalence and determinants of diabetic retinopathy and cataracts in West African type 2 diabetes patients.
OBJECTIVE To quantify the prevalence of, and risk factors for, diabetic retinopathy and cataracts in patients with type 2 diabetes, and their spouse controls, enrolled from 5 centers in 2 WestExpand
  • 80
  • 7
In search of susceptibility genes for type 2 diabetes in West Africa: the design and results of the first phase of the AADM study.
PURPOSE The purpose of this study is to map type 2 diabetes susceptibility genes in West African ancestral populations of African-Americans, through an international collaboration between WestExpand
  • 74
  • 5
Breast cancer genetics in African Americans
An overview of the state of genetic testing for BRCA1 and BRCA2 genes was presented at the Summit Meeting on Breast Cancer Among African American women.
  • 153
  • 4
Extent of linkage disequilibrium between the androgen receptor gene CAG and GGC repeats in human populations: implications for prostate cancer risk
While studies have implicated alleles at the CAG and GGC trinucleotide repeats of the androgen receptor gene with high-grade, aggressive prostate cancer disease, little is known about the normalExpand
  • 91
  • 4
BRCA1 mutations in African Americans
The breast cancer predisposing gene, BRCA1, was analyzed for germline mutations in 45 African American families at high-risk for hereditary breast cancer. Patients were considered high-risk if theyExpand
  • 74
  • 4
Evidence for a BRCA1 founder mutation in families of West African ancestry.
This study was supported by National Institutes of Health grants CA27632, CA55772, and RR03048, by U.S. Department of Defense grant 17-94-J4245, and by grants from the Komen Foundation and theExpand
  • 55
  • 4
Organ donation and blacks. A critical frontier.
The past decade has witnessed an inexorable widening in the gap between the supply of organs for transplantation (i.e., the donors) and the need for organs on the part of desperately ill candidatesExpand
  • 71
  • 3