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- Publications
- Influence
Microbial production of hyaluronic acid: current state, challenges, and perspectives
- L. Liu, Y. Liu, J. Li, G. Du, Jian Jhen Chen
- Biology, Medicine
- Microbial cell factories
- 16 November 2011
Hyaluronic acid (HA) is a natural and linear polymer composed of repeating disaccharide units of β-1, 3-N-acetyl glucosamine and β-1, 4-glucuronic acid with a molecular weight up to 6 million… Expand
A combined physiological and proteomic approach to reveal lactic-acid-induced alterations in Lactobacillus casei Zhang and its mutant with enhanced lactic acid tolerance
- Chongde Wu, J. Zhang, W. Chen, M. Wang, G. Du, J. Chen
- Biology, Medicine
- Applied Microbiology and Biotechnology
- 2011
Lactobacillus casei has traditionally been recognized as a probiotic and frequently used as an adjunct culture in fermented dairy products, where acid stress is an environmental condition commonly… Expand
Optimization and scale-up of propionic acid production by propionic acid-tolerant Propionibacterium acidipropionici with glycerol as the carbon source.
- Yunfeng Zhu, J. Li, +6 authors Jian Jhen Chen
- Chemistry, Medicine
- Bioresource technology
- 1 November 2010
Propionic acid production by Propionibacterium acidipropionici with glycerol as sole carbon source was studied in 7-L batch and 10m(3) bioreactor cultures. In batch cultures, propionic acid… Expand
Aerobic granular sludge cultivated under the selective pressure as a driving force
Inoculated with aerobic sludge from a conventional activated sludge wastewater treatment plant, granulation of aerobic sludge was realized in a sequencing batch reactor fed with glucose as carbon… Expand
Treatment of synthetic wastewater by a novel MBR with granular sludge developed for controlling membrane fouling
- X. Li, Fangshu Gao, Z. Hua, G. Du, Jian Chen
- Chemistry
- 1 November 2005
Abstract A novel membrane bioreactor system, a membrane bioreactor with aerobic granular sludge (MGSBR), was developed to treat municipal wastewater in this paper. The main goal was to control the… Expand
Real-time PCR assays targeting formyltetrahydrofolate synthetase gene to enumerate acetogens in natural and engineered environments.
Acetogens are ubiquitous in many anaerobic habitats and play a very important role in bioconversion and biodegradation of organic compounds. Methods for rapid detection and quantification of… Expand
Purification and characterization of transglutaminase from a newly isolated Streptomyces hygroscopicus
- L. Cui, G. Du, Dongxu Zhang, H. Liu, J. Chen
- Chemistry
- 2007
Transglutaminase (TGase, EC 2.3.2.13) from a Streptomyces hygroscopicus strain isolated from soil was purified from culture broth by ethanol precipitation, followed by successive chromatographies on… Expand
Multivariate modular metabolic engineering of Escherichia coli to produce resveratrol from L-tyrosine.
- Junjun Wu, Peiran Liu, +4 authors J. Chen
- Biology, Medicine
- Journal of biotechnology
- 20 September 2013
Microbial fermentations and bioconversion promise to revolutionize the conventional extraction of resveratrol from natural plant sources. However, the development of efficient and feasible microbial… Expand
Microbial production of propionic acid from propionibacteria: Current state, challenges and perspectives
- L. Liu, Yunfeng Zhu, +4 authors J. Chen
- Chemistry, Medicine
- Critical reviews in biotechnology
- 5 November 2012
Propionic acid (PA) is an important building block chemical and finds a variety of applications in organic synthesis, food, feeding stuffs, perfume, paint and pharmaceutical industries. Presently, PA… Expand
Enhanced alpha-ketoglutaric acid production in Yarrowia lipolytica WSH-Z06 by regulation of the pyruvate carboxylation pathway
- Xiaoxia Yin, C. Madzak, G. Du, J. Zhou, J. Chen
- Biology, Medicine
- Applied Microbiology and Biotechnology
- 9 June 2012
In previous research, a thiamine-auxotrophic yeast for alpha-ketoglutaric acid (KGA) overproduction was screened in our laboratory and named Yarrowia lipolytica WSH-Z06 (CCTCC no. M207143). However,… Expand