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Opiate addicts lack error-dependent activation of rostral anterior cingulate
BACKGROUND Healthy individuals performing response suppression tasks activate anterior cingulate cortex with occurrence of false alarm error responses to nontargets. Fundamental questions includeExpand
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Lipidomics Reveals Early Metabolic Changes in Subjects with Schizophrenia: Effects of Atypical Antipsychotics
There is a critical need for mapping early metabolic changes in schizophrenia to capture failures in regulation of biochemical pathways and networks. This information could provide valuable insightsExpand
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Altered interactions of tryptophan metabolites in first-episode neuroleptic-naive patients with schizophrenia
Schizophrenia is characterized by complex and dynamically interacting perturbations in multiple neurochemical systems. In the past, evidence for these alterations has been collected piecemeal,Expand
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Cerebrospinal Fluid Metabolome in Mood Disorders-Remission State has a Unique Metabolic Profile
Targeted metabolomics provides an approach to quantify metabolites involved in specific molecular pathways. We applied an electrochemistry-based, targeted metabolomics platform to define changes inExpand
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Chronic D-amphetamine in nucleus accumbens: lack of tolerance or reverse tolerance of locomotor activity.
Abstract An experiment was designed to test the ability of chronic intra-accumbens amphetamine injections to produce the augmentation of locomotor activity noted with repeated intraperitonealExpand
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3-Hydroxykynurenine and clinical symptoms in first-episode neuroleptic-naive patients with schizophrenia.
One branch of the tryptophan catabolic cascade is the kynurenine pathway, which produces neurotoxic [3-hydroxykynurenine (3-OHKY), quinolinic acid] and neuroinhibitory (kynurenic acid) compounds.Expand
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Influence of gamma-butyrolactone on behavior due to dopaminergic drugs
Gamma-butyrolactone (GBL) is well known to reduce dopamine neuronal impulse flow, but the effects of the drug on dopamine-dependent behavioral states is not well studied. Qualitative and quantitativeExpand
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Prevalence and Specificity of the Abnormal Niacin Response: A Potential Endophenotype Marker in Schizophrenia
The skin flush response to niacin is abnormally blunted among a subset of patients with schizophrenia (SZ), preferentially associates with SZ compared to other mental illnesses, occurs frequently inExpand
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Associations between Purine Metabolites and Clinical Symptoms in Schizophrenia
Background The antioxidant defense system, which is known to be dysregulated in schizophrenia, is closely linked to the dynamics of purine pathway. Thus, alterations in the homeostatic balance in theExpand
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Processing and morphology of permeable polycrystalline silicon thin films
It is known that thin films of polycrystalline silicon, deposited under the right conditions, can be permeable to HF-based etching solutions. While these films offer unique capabilities forExpand
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