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Proteasome-Mediated Degradation of p21 via N-Terminal Ubiquitinylation
We examined the mechanism responsible for the degradation of p21, a negative regulator of the cell division cycle. We found that p21 proteolysis requires functional ubiquitin and Nedd8 systems.Expand
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Influence of suspension hypokinesia on rat soleus muscle.
Hindlimb hypokinesia was induced in rats by the Morey method to characterize the response of the soleus muscle. Rats suspended for 1-4 wk exhibited continuous and significant declines in soleus mass,Expand
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On the Need for Professional Economic Ethics
In this lead piece of our trilogy, the author argues that economists need to engage the ethics of what they do directly and actively. He presents four compelling propositions for why they must do so.Expand
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Mass spectrometry in structural and stereochemical problems. CCXXXVII—Electron-impact-induced hydrogen losses and migrations in some aromatic amides†
The mass spectra of a series of benzamides and naphthamides have been investigated with respect to their propensity to lose an aromatic hydrogen atom from their molecular ions. Deuterium labeling andExpand
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Varshavsky's Contributions
We are writing to express our enthusiasm that the discovery of the ubiquitin conjugation system has been acknowledged with the award of the Nobel Prize in Chemistry to three outstanding biochemists:Expand
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Beta-endorphins ACTH and cortisol in CSF and plasma of HIV infected patients.
Interactions between HPA (Hypothalamic-pituitary-axis) and immune system seem to involve the EPO (endogenous opioid peptides) system, as shown by some recent findings. Possible relationships betweenExpand
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