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Contractile and Vasorelaxant Effects of Hydrogen Sulfide and Its Biosynthesis in the Human Internal Mammary Artery
- G. D. Webb, L. H. Lim, +12 authors P. Moore
- Journal of Pharmacology and Experimental…
- 1 February 2008
This study aimed to test these hypotheses: cystathionine γ-lyase (CSE) is expressed in a human artery, it generates hydrogen sulfide (H2S), and H2S relaxes a human artery. H2S is produced… Expand
Hydrogen sulfide in the mammalian cardiovascular system.
- Yi-hong Liu, M.-T. Lu, L. Hu, P. Wong, G. D. Webb, J. Bian
- Biology, Medicine
- Antioxidants & redox signaling
- 7 May 2012
For more than a century, hydrogen sulfide (H(2)S) has been regarded as a toxic gas. This review surveys the growing recognition of the role of H(2)S as an endogenous signaling molecule in mammals,… Expand
Biochemical and pharmacological aspects of the synapses of the squid stellate ganglion
Abstract The giant axon and isolated single giant synapses from the squid stellate ganglion were analyzed for acetylcholine (ACh), choline acetylase, and acetylcholinesterase (ACh-esterase). ACh,… Expand
THE EFFECTS OF SURFACTANTS ON THE POTENTIAL, SHORT-CIRCUIT CURRENT, AND ION FLUXES ACROSS THE ISOLATED FROG SKIN.
- G. D. Webb
- Chemistry, Medicine
- Acta physiologica Scandinavica
- 1 March 1965
It has been shown previously that ionic surface active agents (surfactants) depolarize nerve and muscle membranes and the isolated frog skin. The isolated frog skin was used in the present studies.… Expand
Sulfur and selenium isologs related to acetycholine. and choline IV. Activity in the electroplax preparation.
Abstract Studies using the isolated single cell electroplax preparation indicated that the hydrolysis products of acetylthiocholine and acetylselenocholine, cholinethiol and cholineselenol, are… Expand
Affinity of benzoquinonium and ambenonium derivatives for the acetylcholine receptor, tested on the electroplax, and for acetylcholinesterase in solution.
- G. D. Webb
- Chemistry, Medicine
- Biochimica et biophysica acta
- 25 May 1965
Abstract The dissociation constants between certain benzoquinonium and ambenonium analogs and the acetylcholine receptor were determined with the isolated electroplax; they were compared with those… Expand
Sulfur and selenium compounds related to acetylcholine and choline. VI. Effects of homocholine derivatives on the electroplax preparation.
Abstract The depolarizing activities of homocholine, homocholinethiol, homocholineselenol, their acetyl esters, and their methyl derivatives were measured in the single-cell electroplax preparation… Expand
Apparent dissociation constants for several inhibitors of acetylcholinesterase in the intact electroplax of the electric eel.
Abstract Apparent dissociation constants were determined for d -tubocurarine, benzoquinonium, ambenonium, WIN 3286, and WIN 7789 as inhibitors of acetylcholinesterase (AChE) in the intact electroplax… Expand
Rapid desensitization of acetylcholine receptors of eel electroplaques following iontophoretic application of agonist compounds.
1. The electrical potential difference across the innervated membrane of the electroplaque of Electrophorus electricus was measured with an intracellular micro‐electrode while an extracellular… Expand
Effect of insecticides on the short-circuit current and resistance of isolated frog skin
Abstract The effects of aldrin, carbaryl, α- and γ-chlordane, dichlorodiphenyldichloroethane (DDD), dichlorodiphenyltrichloroethane (DDT), dieldrin, endrin, heptachlor, lindane, methoxychlor, and… Expand