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Matrix metalloproteinase-25 has a functional role in mouse secondary palate development and is a downstream target of TGF-β3
BackgroundDevelopment of the secondary palate (SP) is a complex event and abnormalities during SP development can lead to cleft palate, one of the most common birth disorders. MatrixExpand
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Intravenous administration of human embryonic stem cell‐derived neural precursor cells attenuates cuprizone‐induced central nervous system (CNS) demyelination
S. J. Crocker, R. Bajpai, C. S. Moore, R. F. Frausto, G. D. Brown, R. R. Pagarigan, J. L. Whitton and A. V. Terskikh (2011) Neuropathology and Applied Neurobiology37, 643–653
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The predicted truncation from a cancer‐associated variant of the MSH2 initiation codon alters activity of the MSH2‐MSH6 mismatch repair complex
Lynch syndrome (LS) is caused by germline mutations in DNA mismatch repair (MMR) genes. MMR recognizes and repairs DNA mismatches and small insertion/deletion loops. Carriers of MMR gene variantsExpand
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MMP‐3 mediates psychosine‐induced globoid cell formation: Implications for leukodystrophy pathology
Globoid cell leukodystrophy (GLD) or Krabbe disease, is a fatal demyelinating disease attributed to mutations in the galactocerebrosidase (GALC) gene. Loss of function mutations in GALC result inExpand
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Radiolabelled tracers and anticancer drugs for assessment of therapeutic efficacy using PET.
Positron Emission Tomography (PET) has the potential to improve efficacy of established and novel cancer therapies and to assist more rapid and rational progression of promising novel therapies intoExpand
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