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Diffusion Coefficients for the Binary System Glycerol + Water at 25 °C. A Velocity Correlation Study
Diffusion coefficients for the binary system glycerol + water have been studied at 25 °C. Accurate mutual diffusion coefficients have been measured by the Taylor dispersion and Gouy interferometricExpand
Chemistry of lipid A: at the heart of innate immunity.
The chemical aspects regarding lipid A and its role in innate immunity are described and discussed, from the (bio)synthesis, isolation and characterization to the molecular recognition at the atomic level. Expand
Covalently linked hopanoid-lipid A improves outer-membrane resistance of a Bradyrhizobium symbiont of legumes.
It is demonstrated that a photosynthetic Bradyrhizobium strain, symbiont of Aeschynomene legumes, synthesizes a unique LPS bearing a hopanoid covalently attached to lipid A that reinforces the stability and rigidity of the outer membrane. Expand
Red human hair pheomelanin is a potent pro‐oxidant mediating UV‐independent contributory mechanisms of melanomagenesis
The unprecedented property of purified red human hair pheomelanin (RHP) is disclosed to promote the oxygen‐dependent depletion of major cell antioxidants, for example glutathione and NADH; and the autoxidative formation of melanin pigments from their precursors. Expand
Interaction between Alzheimer's Abeta(25-35) peptide and phospholipid bilayers: the role of cholesterol.
The results show that Abeta(25-35) inserts in bilayers formed by the zwitterionic phospholipid dilauroyl phosphatidylcholine (DLPC), positioning between the outer part of the hydrophobic core and the external hydrophilic layer, indicating the peptide insertion to be driven by hydrophobia rather than electrostatic interactions. Expand
Clickable functionalization of liposomes with the gH625 peptide from Herpes simplex virus type I for intracellular drug delivery.
Results suggest that liposomes functionalized with gH625 may act as promising intracellular targeting carriers for efficient delivery of drugs, such as chemotherapeutic agents, into tumor cells. Expand
Structural characterization of the transmembrane proximal region of the hepatitis C virus E1 glycoprotein.
The experimental data support the idea that this region of E1 might be involved in membrane destabilization and viral fusion; therefore, it may represent a good target to develop anti-viral molecules. Expand
Effect of flavonoids on the Abeta(25-35)-phospholipid bilayers interaction.
An Electron Paramagnetic Resonance investigation of 2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) membranes interacting with the beta-amyloid fragment Abeta is reported, evidencing a flavonoid-dependent rigidifying effect of the bilayer, which may provide the molecular basis to explain the known neuroprotective effect of flavonoids. Expand
Physicochemical properties of mixed micellar aggregates containing CCK peptides and Gd complexes designed as tumor specific contrast agents in MRI.
The mixed aggregates as well as the pure C18DTPAGlu aggregate, in the presence and absence of Gd, have been fully characterized by surface tension measurements, FT-PGSE-NMR, fluorescence quenching, and small-angle neutron scattering measurements. Expand