• Publications
  • Influence
Paradigm shifts in heart-failure therapy--a timeline.
As we enter a new era of treatment for heart failure with reduced ejection fraction, historical perspective is provided in a timeline (at NEJM.org) of 26 randomized, controlled trials inExpand
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Drug-eluting coronary stents--promise and uncertainty.
When a potentially serious albeit uncommon complication such as stent thrombosis is detected, it is mandatory that everything possible be done to aggressively examine the complication, assess theExpand
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Hypothermia to protect the brain.
  • G. Curfman
  • Medicine
  • The New England journal of medicine
  • 21 February 2002
For decades, cooling the body below the normal physiologic temperature has been used as a therapeutic tool. Hypothermia is used most often during cardiac surgery with cardiopulmonary bypass, as aExpand
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A new look at cardiac exercise testing.
Since the introduction of treadmill exercise testing by Robert Bruce five decades ago, graded exercise testing has been a cornerstone of diagnostic procedures for coronary artery disease. An articleExpand
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Civil Litigation and the Opioid Epidemic: The Role of Courts in a National Health Crisis
The devastating impact of the national opioid epidemic has given rise to hundreds of lawsuits. This article details the extremely broad range of legal claims, compares the opioid cases to otherExpand
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Sustained effectiveness of converting-enzyme inhibition in patients with severe congestive heart failure.
Eight patients with severe congestive heart failure refractory to conventional therapy, including vasodilators, were given captopril (seven patients) or teprotide (one patient). All had dyspnea,Expand
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Expression of concern: Bombardier et al., "Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis," N Engl J Med 2000;343:1520-8.
Drs. Gregory Curfman, Stephen Morrissey, and Jeffrey Drazen report on recently obtained information regarding inaccuracies in data in the report of the Vioxx Gastrointestinal Outcomes Research studyExpand
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The health benefits of exercise. A critical reappraisal.
  • G. Curfman
  • Medicine
  • The New England journal of medicine
  • 25 February 1993
In his 1772 account of angina pectoris, the English physician William Heberden described a patient who “set himself a task of sawing wood for half an hour every day, and was nearly cured”1. More re...
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Full disclosure and the funding of biomedical research.
Clinical studies have become very expensive to conduct, and multiple sources of funding often support a single study. Biomedical journals routinely disclose all sources of funding of the researchExpand
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Human papillomavirus vaccine--opportunity and challenge.
In this issue of the Journal, we publish three Original Articles,1–3 two Perspective articles,4,5 two editorials,6,7 a letter to the editor,8 and an audio interview9 on the subject of humanExpand
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