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Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage
  • Guorong Li, G. Cui, +4 authors J. Hong
  • Chemistry, Medicine
  • FASEB journal : official publication of the…
  • 1 April 2005
Inflammation in the brain has increasingly been recognized to play an important role in the pathogenesis of several neurodegenerative disorders, including Parkinson's disease (PD). Progress in theExpand
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Study on the ecological distribution of alveolar Echinococcus in Hulunbeier Pasture of Inner Mongolia, China.
A study on the ecological distribution of alveolar Echinococcus was carried out in the Hulunbeier Pasture of Inner Mongolia, China during 1998 and 1999. Animals examined included wolves (CanisExpand
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Current epidemiological profile and features of visceral leishmaniasis in people's republic of China
BackgroundVisceral leishmaniasis (VL) is still an important public health problem in China. In recent years endemic regions spread, prevalence increased, and even an outbreak of the disease occurredExpand
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Cyclic AMP Response Element Modulator-1 (CREM-1) Involves in Neuronal Apoptosis after Traumatic Brain Injury
The cyclic AMP response element-binding protein (CREB) family can regulate biological functions of various types of cells by forming homo- or heterodimers to bind the target DNA sequences; it playsExpand
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Different Functions of HIPK2 and CtBP2 in Traumatic Brain Injury
Traumatic brain injury (TBI) initiates a complex series of neurochemical and signaling changes that lead to neuronal dysfunction and over-reactive astrocytes. In our study, homeodomain interactingExpand
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A One-Step Homogeneous Sandwich Immunosensor for Salmonella Detection Based on Magnetic Nanoparticles (MNPs) and Quantum Dots (QDs)
Simple immuno-magnetic separation tandem fluorescent probes based on quantum dots-antibody (QDs-Ab) were developed to detect Salmonella with sensitivity of 500 cfu mL−1. With two monoclonalExpand
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Protective effect of dextromethorphan against endotoxic shock in mice.
Dextromethorphan (DM) is a dextrorotatory morphinan and an over-the-counter non-opioid cough suppressant. We have previously shown that DM protects against LPS-induced dopaminergic neurodegenerationExpand
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miRNA-149* promotes cell proliferation and suppresses apoptosis by mediating JunB in T-cell acute lymphoblastic leukemia.
MicroRNA-149* (miRNA-149*) functions as an oncogenic regulator in human melanoma. However, the effect of miRNA-149* on T-cell acute lymphoblastic leukemia (T-ALL) is unclear. Here we aimed to analyzeExpand
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Clinical and biological significance of Nemo-like kinase expression in glioma
Nemo-like kinase (NLK) is an evolutionarily conserved serine/threonine kinase that suppresses the transcriptional activity of β-catenin/T-cell factor complex through phosphorylation of T-cell factor.Expand
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Upregulation of CRM1 Relates to Neuronal Apoptosis after Traumatic Brain Injury in Adult Rats
Traumatic brain injury (TBI) initiates a complex series of neurochemical and signaling changes that leads to neuronal dysfunction and over-reactive astrocytes. There is increasing evidence that CRM1Expand
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