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Pharmacokinetic properties of enrofloxacin in rabbits.
- R. Broome, D. L. Brooks, J. Babish, D. Copeland, G. Conzelman
- American journal of veterinary research
The pharmacokinetic properties of the fluoroquinolone antimicrobial enrofloxacin were studied in New Zealand White rabbits. Four rabbits were each given enrofloxacin as a single 5 mg/kg of body… Expand
Dose-response relationships of the bladder tumorigen 2-naphthylamine: a study in beagle dogs.
Gentamicin Nephrotoxicity in the Dog: Sequential Light and Electron Microscopy
Sequential percutaneous renal biopsies in six dogs given gentamicin at 10 mg/kg every 8 hours (intramuscular) were examined before treatment and 5, 9 and 12 days after treatment. Renal function tests… Expand
Frusemide enhancement of netilmicin nephrotoxicity in dogs.
The influence of the anatomic locationof a tumor on its susceptibility to chemotherapy.
On the physiologic disposition of cycloserine in experimental animals.
N-oxidation of certain aromatic amines, acetamides, and nitro compounds by monkeys and dogs.
Furosemide enhancement of experimental gentamicin nephrotoxicity: comparison of functional and morphological changes with activities of urinary enzymes.
- R. Adelman, W. Spangler, F. Beasom, G. Ishizaki, G. Conzelman
- Chemistry, Medicine
- The Journal of infectious diseases
- 1 September 1979
Dogs were given gentamicin (10 mg/kg) intramuscularly every 8 hr for 10 days. Levels of serum creatinine rose by day 6 (0.91 +/- 0.08 vs. 0.75 +/- 0.02 mg/dl for controls, P less than 0.05) and of… Expand
Beta-glucuronidase, sulfatase, and phosphatase activities in the urine of dogs, monkeys, and mice.