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Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization.
TLDR
An independent, graded association was observed between a reduced estimated GFR and the risk of death, cardiovascular events, and hospitalization in a large, community-based population and highlights the clinical and public health importance of chronic renal insufficiency. Expand
Mineral metabolism, mortality, and morbidity in maintenance hemodialysis.
TLDR
Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia. Expand
Acute kidney injury, mortality, length of stay, and costs in hospitalized patients.
TLDR
Modest changes in SCr were significantly associated with mortality, LOS, and costs, even after adjustment for age, gender, admission International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis, severity of illness (diagnosis-related group weight), and chronic kidney disease. Expand
Metabolic syndrome and the risk for chronic kidney disease among nondiabetic adults.
TLDR
The metabolic syndrome is independently associated with an increased risk for incident CKD in nondiabetic adults and this study found that those with one, two, three, four, or five traits of the metabolic syndrome had a higher risk of developing CKD than others. Expand
Independent association between acute renal failure and mortality following cardiac surgery.
TLDR
Acute renal failure was independently associated with early mortality following cardiac surgery, even after adjustment for comorbidity and postoperative complications. Expand
Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients.
TLDR
Compared with calcium-based phosphate binders, sevelamer is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients. Expand
Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years: A Randomized Clinical Trial.
TLDR
Among ambulatory adults aged 75 years or older, treating to an SBP target of less than 120 mm Hg compared with an SBp target of more than 140mm Hg resulted in significantly lower rates of fatal and nonfatal major cardiovascular events and death from any cause. Expand
Spectrum of acute renal failure in the intensive care unit: the PICARD experience.
TLDR
There is a changing spectrum of ARF in the critically ill, characterized by a large burden of comorbid disease and extensive extrarenal complications, obligating the need for dialysis in the majority of patients. Expand
Intensity of renal support in critically ill patients with acute kidney injury.
TLDR
Intensive renal support in critically ill patients with acute kidney injury did not decrease mortality, improve recovery of kidney function, or reduce the rate of nonrenal organ failure as compared with less-intensive therapy. Expand
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