Insertional inactivation of the p53 gene during friend leukemia: a new strategy for identifying tumor suppressor genes.
- Y. Ben-David, A. Lavigueur, G. Cheong, A. Bernstein
- Biology, Medicine
- The New biologist
- 1 November 1990
Rearrangements within the p53 gene are observed in a high proportion of independent erythroleukemic cell lines derived from the spleens of mice infected with Friend leukemia virus. The majority of… Expand
Temporal order and functional analysis of mutations within the Fli-1 and p53 genes during the erythroleukemias induced by F-MuLV.
The erythroleukemias induced by Friend murine leukemia virus (F-MuLV) result from the accumulation of a number of genetic changes, including activation of the Fli-1 proto-oncogene and inactivation of… Expand