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Aspergicin, a new antibacterial alkaloid produced by mixed fermentation of two marine-derived mangrove epiphytic fungi
- F. Zhu, G. Chen, X. Chen, Meizhen Huang, Xueqin Wan
- Chemistry of Natural Compounds
- 14 December 2011
A new alkaloid designated as aspergicin (1), together with a previous secondary metabolite, neoaspergillic acid (2), and a common compound, ergosterol (3), were isolated from the mixed cultured… Expand
Two new dihydroisocoumarins from the endophytic fungus Aspergillus sp. collected from the south china sea
Two new dihydroisocoumarin derivatives, aspergillumarins A and B (1 and 2), were isolated from the culture broth of a marine-derived fungus Aspergillus sp., which was isolated from the fresh leaf of… Expand
Molecular evidence of cryptotanshinone for treatment and prevention of human cancer.
- W. Chen, Yin Lu, G. Chen, Shile Huang
- Anti-cancer agents in medicinal chemistry
- 31 August 2013
Cryptotanshinone is one of the major tanshinones isolated from the roots of the plant Salvia miltiorrhiza Bunge (Danshen). Danshen has been widely used in traditional Chinese medicine for treatment… Expand
Chemical constituents from the roots of Xanthium sibiricum
Xanthium sibiricum patrin ex Widder (Compositae) is an annual herb which grows all around China. Chemical investigations of its roots resulted in the identification of 15 compounds:… Expand
The genetic algorithm based back propagation neural network for MMP prediction in CO2-EOR process
In this study, a genetic algorithm based back propagation artificial neural network model was developed and used to predict the minimum miscibility pressure, i.e. MMP, for both pure and impure CO2… Expand
Structure revision and cytotoxic activity of marinamide and its methyl ester, novel alkaloids produced by co-cultures of two marine-derived mangrove endophytic fungi
Marinamide (1) and its methyl ester (2) have been previously reported as pyrrolyl 1-isoquinolone alkaloids, which were produced by co-cultures of two marine-derived mangrove endophytic fungi from the… Expand
(+/-)-3'-O, 4'-O-dicynnamoyl-cis-khellactone, a derivative of (+/-)-praeruptorin A, reverses P-glycoprotein mediated multidrug resistance in cancer cells.
P-glycoprotein (Pgp) is an ATP-driven membrane exporter for a broad spectrum of hydrophobic xenobiotics. Pgp-overexpression is a common cause of multidrug resistance (MDR) in cancer cells and could… Expand
Heteropolyanion-Based Ionic Liquid for Deep Desulfurization of Fuels in Ionic Liquids
A heteropolyanion-based ionic liquid, [(3-sulfonic acid) propylpyridine]3PW12O40·2H2O, [PSPy]3PW12O40·2H2O, abbreviated [PSPy]3PW, was synthesized and approved as an effective catalyst for… Expand
Cytotoxic effects of procyanidins from Castanea mollissima Bl. shell on human hepatoma G2 cells in vitro.
- H. Zhang, J. Ke, +7 authors X. Sun
- Chemistry, Medicine
- Food and chemical toxicology : an international…
- 1 February 2014
Significant cytotoxic effects of procynadins from chestnut (Castanea mollissima Bl.) shell (CSPC) on human hepatoma G2 (HepG2) cells were found in vitro. CSPC could inbibit HepG2 proliferation in a… Expand
Design, synthesis and biological evaluation of lazabemide derivatives as inhibitors of monoamine oxidase.
- Shiyang Zhou, G. Chen, Gangliang Huang
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 15 September 2018
In the studied a series novel of lazabemide derivatives were designed, synthesized and evaluated as inhibitors of monoamine oxidase (MAO-A or MAO-B). These compounds used lazabemide as the lead… Expand