Share This Author
Human Dental pulp stem cells (hDPSCs): isolation, enrichment and comparative differentiation of two sub-populations
This study characterized and compared two subpopulations of adult stem cells derived from human dental pulp, and suggested that STRO-1+/c-Kit+/CD34− hDPSCs and STROs might represent two distinct stem cell populations, with different properties.
Human Serum Promotes Osteogenic Differentiation of Human Dental Pulp Stem Cells In Vitro and In Vivo
It is demonstrated that human serum (HS) is a suitable alternative to FCS, indeed its addition to culture medium induces a high hDPSCs proliferation rate and improves the in vitro osteogenic differentiation.
Inhibition of Lon protease by triterpenoids alters mitochondria and is associated to cell death in human cancer cells
The overexpression of Lon can rescue cells from cell death, providing an additional evidence on the role of Lon in conditions of excessive stress load.
Sirtuin 3 interacts with Lon protease and regulates its acetylation status.
Effects of different doses of ferutinin on bone formation/resorption in ovariectomized rats
- F. Cavani, M. Ferretti, G. Carnevale, L. Bertoni, M. Zavatti, C. Palumbo
- Biology, MedicineJournal of Bone and Mineral Metabolism
- 25 July 2012
The results suggest that the role of ferutinin in preventing osteoporosis caused by estrogen deficiency is expressed in decreasing bone erosion; moreover, in all F-OVX groups bone turnover is very low and seems correlated to the trivial body weight increase, which, in turn, depends on ferut inin treatment.
Human dental pulp stem cells expressing STRO‐1, c‐kit and CD34 markers in peripheral nerve regeneration
- G. Carnevale, A. Pisciotta, A. Pol
- Biology, MedicineJournal of tissue engineering and regenerative…
- 1 February 2018
It is demonstrated that STRO‐1+/c‐Kit+/CD34+ hDPSCs, associated with neural crest derivation, represent a promising source of stem cells for the treatment of demyelinating disorders and might provide a valid alternative tool for future clinical applications to achieve functional recovery after injury or peripheral neuropathies besides minimizing ethical issues.
Structural and histomorphometric evaluations of ferutinin effects on the uterus of ovariectomized rats during osteoporosis treatment.
Neural crest derived stem cells from dental pulp and tooth-associated stem cells for peripheral nerve regeneration
- A. Pisciotta, L. Bertoni, Antonio Vallarola, G. Bertani, D. Mecugni, G. Carnevale
- Biology, MedicineNeural regeneration research
- 26 September 2019
The literature concerning the application of tooth derived stem cell populations combined with different conduits to peripheral nerve injuries animal models is reviewed, highlighting their regenerative contribution exerted through either glial differentiation and neuroprotective/neurotrophic effects on the host tissue.
Human amniotic fluid-derived and dental pulp-derived stem cells seeded into collagen scaffold repair critical-size bone defects promoting vascularization
These data confirmed the strong potential of bioengineered constructs of stem cell–collagen scaffold for correcting large cranial defects in an animal model and highlighting the role of stem cells in neovascularization during skeletal defect reconstruction.
Stem cells isolated from human dental pulp and amniotic fluid improve skeletal muscle histopathology in mdx/SCID mice
This study shows that hAFSCs and hDPSCs represent potential sources of stem cells for translational strategies to improve the histopathology and potentially alleviate the muscle weakness in patients with DMD.