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Further brominated bis- and tris-indole alkaloids from the deep-water New Caledonian marine sponge Orina Sp.
Two tris-indole alkaloids have been isolated for the first time from a marine source, the New Caledonian sponge, and showed anti-serotonin activity and a strong affinity for somatostatin and neuropeptide Y receptors in receptor-binding assays. Expand
Naturally occurring somatostatin and vasoactive intestinal peptide inhibitors. Isolation of alkaloids from two marine sponges.
The vasoactive intestinal peptide (VIP) and somatostatin (somatotropin release inhibiting factor, SRIF) are important neurotransmitters in a number of basic physiological events. Their disturbancesExpand
Flavonoids from Alphitonia neocaledonica.