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Depletion of a single nucleoporin, Nup107, prevents the assembly of a subset of nucleoporins into the nuclear pore complex
The nuclear pore complex (NPC) is a protein assembly that contains several distinct subcomplexes. The mammalian nucleoporin (Nup)-107 is part of a hetero-oligomeric complex, that also containsExpand
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Role of signal recognition particle in the membrane assembly of Sindbis viral glycoproteins.
We have investigated the role of signal recognition particle (SRP) in the biosynthesis of Sindbis glycoproteins by translating the viral 26S mRNA in a wheat-germ cell-free system. SRP was shown toExpand
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The β-Subunit of the Protein-conducting Channel of the Endoplasmic Reticulum Functions as the Guanine Nucleotide Exchange Factor for the β-Subunit of the Signal Recognition Particle Receptor*
Cotranslational protein transport to the endoplasmic reticulum is controlled by the concerted interaction of three GTPases: the SRP54 subunit of the signal recognition particle (SRP) and the α- andExpand
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Standing Up for GMOs
On 8 August 2013, vandals destroyed a Philippine “Golden Rice” Field Trial. Officials and staff of the Philippine Department of Agriculture that conduct rice tests for the International Rice ResearchExpand
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Primary structure and genomic organization of the histidine-rich protein of the malaria parasite Plasmodium lophurae
The nucleotide sequence of a complete genomic clone for the histidine-rich protein of Plasmodium lophurae has been determined. The deduced amino acid sequence of the mature protein shows numerousExpand
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Intracellular protein topogenesis ( protein translocation across membranes / protein integration into membranes / posttranslocational sorting / topogenic sequences / phylogeny of membranes and
Concurrently with or shortly after their synthesis on ribosomes, numerous specific proteins are unidirectionally translocated across or asymmetrically integrated into distinct cellular membranes.Expand
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Import receptor in chloroplast envelope
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Required for Integration into Microsomal Membranes of Calcium Mechanisms of Integration of de novo-Synthesized Polypeptides into Membranes :
We have investigated the in vitro integration into dog pancreas microsomal membranes of three integral membrane proteins that were synthesized de novo in a wheat germ cell-free translation system:Expand
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Assemb L Ed Polysomes Synthesizing Secretory Protein
An 11S protein composed of six polypept ide chains was previously pur i f ied from a salt extract of dog pancreas microsomal membranes and shown to be requi red for translocat ion of nascentExpand
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