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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
TLDR
There continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes, so it is important to update guidelines for monitoring autophagic activity in different organisms.
Inhibition of NF-kappaB activity by BAY 11-7082 increases apoptosis in multidrug resistant leukemic T-cell lines.
Multidrug resistance (MDR) is the main reason for failure of cancer therapy with resistance to apoptosis being one of the mechanisms involved. Constitutive NF-kappaB activity has been detected in
Inhibition of NF-κB activity by BAY 11-7082 increases apoptosis in multidrug resistant leukemic T-cell lines
Multidrug resistance (MDR) is the main reason for failure of cancer therapy with resistance to apoptosis being one of the mechanisms involved. Constitutive NF-kappaB activity has been detected in
Inactivation of Escherichia coli, Listeria innocua and Saccharomyces cerevisiae by UV-C light: Study of cell injury by flow cytometry
TLDR
The results showed that mechanisms of cellular damage differed according to time of exposure to ultraviolet radiation and the organism tested, and FCM was used to detect the inactivation of those L. innocua sub-populations of viable microorganisms which were non-culturable due to membrane rupture and thus not detectable by viable plate count technique.
Hyaluronan oligosaccharides sensitize lymphoma resistant cell lines to vincristine by modulating P‐glycoprotein activity and PI3K/Akt pathway
TLDR
It is reported for the first time that oHA per se modulate MDR in lymphoma cells by decreasing p‐Akt as well as Pgp activity, thus suggesting that o HA could be useful in combination with classical chemotherapy in MDR hematological malignancies.
Condition-dependent immune defence in the Magpie: how important is ectoparasitism?
TLDR
Results are consistent with the hypotheses of condition-dependent investment in the immune system and sexual differences in susceptibility to parasite effects, and ectoparasites may play a role in modulating the relationship between condition and immune defence.
Caffeic acid phenylethyl ester and MG132, two novel nonconventional chemotherapeutic agents, induce apoptosis of human leukemic cells by disrupting mitochondrial function
TLDR
The results indicate that CAPE and MG132 treatment of PL104 cells induced apoptosis through the mitochondrial intrinsic pathway, whereas the apoptotic mechanism induced by DOX and VCR may proceed through the extrinsic pathway.
LPS-induced stimulation of phagocytosis in the sipunculan worm Themiste petricola: possible involvement of human CD14, CD11B and CD11C cross-reactive molecules.
TLDR
The presence, in sipunculan coelomocytes, of antigens cross-reactive with CD14, the alpha chain of CR3 and of p150,95 raises the possibility that molecules related, although not necessary homologous, to the mammalian counterparts may have a role in the defense systems of these animals.
Modulation of matrix metalloproteinase-9 activity by hyaluronan is dependent on NF-kappaB activity in lymphoma cell lines with dissimilar invasive behavior.
TLDR
Results showed that MMP-9 activity modulated by HA through NF-kappaB signaling pathway may be involved in the aggressive behavior of LBLa.
Trichinella infection in wild boars (Sus scrofa) from a protected area of Argentina and its relationship with the presence of humans.
TLDR
The results showed the circulation of Trichinella spiralis in wild boars with a low parasite burden, and suggest the influence of human behavior on the transmission.
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