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The pharmacology of the antioxidant lipoic acid.
Reduction of lipoic acid by lipoamide dehydrogenase.
The role of lipoic acid in the treatment of diabetic polyneuropathy.
Reaction of lipoic acid with ebselen and hypochlorous acid.
Combined Non-Enzymatic and Enzymatic Reduction Favors Bioactivation of Racemic Lipoic Acid: An Advantage of a Racemic Drug?
It is suggested that racemic lipoic acid can be therapeutically more active than the separate enantiomers, which can explain the higher antioxidant activity of racemic Lipoic Acid found in vivo.
The influence of three grazing systems ons ams performance
Pasturing is common practice in The Netherlands and has several advantages. Feeding costs are lower compared to zero-grazing, animal health and welfare benefits from an outdoor period and public…
Strategies to improve the capacity of an automatic milking system
Lipoic acid favors thiolsulfinate formation after hypochlorous acid scavenging: a study with lipoic acid derivatives.
The present results show an antioxidant activity of the metabolites tetranor- and bisnorlipoic acid, which may enhance the reactivity toward HOCl compared to less strained disulfides, resulting in the formation a thiolsulfinate.
An overview of lipoate chemistry.
Effects of dihydrolipoic acid on peptide methionine sulfoxide reductase. Implications for antioxidant drugs.
- G. Biewenga, D. Veening-Griffioen, A. J. Nicastia, G. Haenen, A. Bast
- 1 February 1998
By showing that dihydrolipoic acid (DHLA) reactivates oxidatively damaged alpha-1 antiprotease (alpha 1-AP), a new antioxidant property of DHLA is described. For the first time, it is shown that a…