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- Publications
- Influence
Effects of quinolinic acid-induced lesions of the nucleus accumbens core on inter-temporal choice: a quantitative analysis
- G. Bezzina, T. Cheung, +6 authors I. Anderson
- Psychology, Medicine
- Psychopharmacology
- 22 July 2007
RationaleThere is evidence that lesions of the nucleus accumbens core (AcbC) promote preference for smaller earlier reinforcers over larger delayed reinforcers in inter-temporal choice paradigms. It… Expand
Effect of disconnecting the orbital prefrontal cortex from the nucleus accumbens core on inter-temporal choice behaviour: A quantitative analysis
- G. Bezzina, S. Body, +5 authors J. Deakin
- Psychology, Biology
- Behavioural Brain Research
- 22 August 2008
Previous experiments showed that destruction of the orbital prefrontal cortex (OPFC) or the nucleus accumbens core (AcbC) in rats altered choice between two delayed food reinforcers. Application of a… Expand
Comparison of the effects of 2,5-dimethoxy-4-iodoamphetamine and D-amphetamine on the ability of rats to discriminate the durations and intensities of light stimuli
- C. Hampson, S. Body, +6 authors E. Szabadi
- Chemistry, Medicine
- Behavioural pharmacology
- 1 February 2010
Rats' ability to discriminate durations is disrupted by the monoamine-releasing agent D-amphetamine and the 5-HT2 receptor agonist 2,5-dimethoxy-4-iodoamphetamine (DOI). It is unknown whether this… Expand
Effect of quinolinic acid-induced lesions of the subthalamic nucleus on performance on a progressive-ratio schedule of reinforcement: A quantitative analysis
- G. Bezzina, F.S. den Boon, +6 authors J. Deakin
- Psychology, Medicine
- Behavioural Brain Research
- 22 December 2008
The subthalamic nucleus (STN), a major relay in the indirect striatofugal pathway, plays an important role in extrapyramidal motor control. Recent evidence indicates that it may also be involved in… Expand
Evidence for a role of D1 dopamine receptors in d-amphetamine’s effect on timing behaviour in the free-operant psychophysical procedure
- T. Cheung, G. Bezzina, +4 authors E. Szabadi
- Psychology, Medicine
- Psychopharmacology
- 15 March 2006
RationaleTemporal differentiation of operant behaviour is sensitive to dopaminergic manipulations. Studies using the fixed-interval peak procedure implicated D2 dopamine receptors in these effects.… Expand
Effects of d-amphetamine and DOI (2,5-dimethoxy-4-iodoamphetamine) on timing behavior: interaction between D1 and 5-HT2A receptors
- S. Body, T. Cheung, +5 authors E. Szabadi
- Chemistry, Medicine
- Psychopharmacology
- 19 October 2006
RationaleThe dopamine-releasing agent d-amphetamine and the 5-HT2 receptor agonist 2,5-dimethoxy-4-iodoamphetamine (DOI) have similar effects on free-operant timing behavior. The selective D1… Expand
Effect of quinolinic acid-induced lesions of the nucleus accumbens core on performance on a progressive ratio schedule of reinforcement: implications for inter-temporal choice
- G. Bezzina, S. Body, +5 authors C. Bradshaw
- Psychology, Medicine
- Psychopharmacology
- 3 January 2008
RationaleThe nucleus accumbens core (AcbC) is believed to contribute to the control of operant behaviour by reinforcers. Recent evidence suggests that it is not crucial for determining the incentive… Expand
Evidence for the sensitivity of operant timing behaviour to stimulation of D1 dopamine receptors
- T. Cheung, G. Bezzina, +4 authors E. Szabadi
- Psychology, Medicine
- Psychopharmacology
- 1 August 2007
RationaleTemporal differentiation of operant behaviour is sensitive to dopaminergic manipulations. Previous studies using the fixed-interval peak procedure implicated D2-like dopamine receptors in… Expand
Evidence that the effect of 5-HT2 receptor stimulation on temporal differentiation is not mediated by receptors in the dorsal striatum
- S. Body, K. Asgari, T. Cheung, G. Bezzina, E. Szabadi
- Biology, Medicine
- Behavioural Processes
- 28 February 2006
5-HT2 receptor stimulation alters temporal differentiation in free-operant timing schedules. The anatomical location of the receptor population responsible for this effect is unknown. We examined the… Expand
Quantitative analysis of the effect of lesions of the subthalamic nucleus on intertemporal choice: further evidence for enhancement of the incentive value of food reinforcers
- G. Bezzina, T. Cheung, +4 authors E. Szabadi
- Psychology, Medicine
- Behavioural pharmacology
- 1 September 2009
Recent evidence suggests that the subthalamic nucleus (STN) is involved in regulating the incentive value of food reinforcers. The objective of this study was to examine the effect of lesions of the… Expand