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Infective endocarditis in hypertrophic cardiomyopathy: prevalence, incidence, and indications for antibiotic prophylaxis.
TLDR
Endocarditis in HCM is virtually confined to patients with outflow obstruction and is more common in those with both obstruction and atrial dilatation, and antibiotic prophylaxis is required only in patients with obstructive HCM.
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Serum Uric Acid and Target Organ Damage in Primary Hypertension
TLDR
The role of serum uric acid as an independent risk factor for cardiovascular and renal morbidity is supported and its relationship with preclinical organ damage is understood to help clarify the mechanism(s) implicated in the development of early cardiovascular disease.
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Cardiac magnetic resonance imaging detects subclinical right ventricular impairment in systemic sclerosis.
TLDR
Unlike standard diagnostic techniques, cardiac MRI appears to be a rapid and noninvasive means of determining subclinical right myocardial involvement that is otherwise undetected in patients with SSc.
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Functional tricuspid regurgitation: an underestimated issue.
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Comparison of sulfur hexafluoride microbubble (SonoVue)-enhanced myocardial contrast echocardiography with gated single-photon emission computed tomography for detection of significant coronary…
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Testosterone Antagonizes Doxorubicin‐Induced Senescence of Cardiomyocytes
TLDR
Testosterone protects cardiomyocytes against senescence caused by doxorubicin at least in part by modulating telomere binding factor 2 via a pathway involving the androgen receptor, phosphatidylinositol 3 kinase, AKT, and nitric oxide synthase 3.
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Mild Renal Dysfunction and Subclinical Cardiovascular Damage in Primary Hypertension
TLDR
Investigating the relation between mild renal dysfunction and subclinical cardiovascular organ damage in 358 never previously treated patients with primary hypertension found that the risk of left ventricular hypertrophy and/or carotid atherosclerosis increased by 43% with each SD reduction in creatinine clearance, and by 89% withEach SD increase in albuminuria.
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Blunted coronary flow reserve in systemic sclerosis.
TLDR
CFR was lower in patients with dSSc than in those affected by lSSc, and should be considered an indirect sign of heart involvement in scleroderma, but its clinical and prognostic implications need to be clarified.
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Role of advanced oxidation protein products and Thiol ratio in patients with acute coronary syndromes.
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Brachial Artery Endothelial-dependent Flow-mediated Dilation Identifies Early-stage Endothelial Dysfunction in Systemic Sclerosis and Correlates with Nailfold Microvascular Impairment
TLDR
The simultaneous presence of macrovascular and microvascular impairment in patients with SSc, which was already present in the early phase of the vascular disease, was demonstrated.
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