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In vitro assessment of cellular immunity in human coccidioidomycosis: relationship between dermal hypersensitivity, lymphocyte transformation, and lymphokine production by peripheral blood…
- N. Ampel, G. Bejarano, S. D. Salas, J. Galgiani
- Medicine, BiologyThe Journal of infectious diseases
- 1 April 1992
It is indicated that healthy individuals with dermal hypersensitivity to Coccidioides immitis can be distinguished from those without hypersensitivity by their cellular in vitro response to a coccidioidal antigen.
Deferoxamine increases the susceptibility of beta-thalassemic, iron-overloaded mice to infection with Listeria monocytogenes.
Killing of Coccidioides immitis by human peripheral blood mononuclear cells
The results suggest that MNL have an inherent ability to kill coccidioidal arthroconidia in vitro which is not dependent on prior host exposure to C. immitis and appears to reside in peripheral blood monocytes.