• Publications
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Jalview Version 2—a multiple sequence alignment editor and analysis workbench
Summary: Jalview Version 2 is a system for interactive WYSIWYG editing, analysis and annotation of multiple sequence alignments. Core features include keyboard and mouse-based editing, multiple viewsExpand
  • 5,260
  • 449
  • Open Access
The Jalview Java alignment editor
Multiple sequence alignment remains a crucial method for understanding the function of groups of related nucleic acid and protein sequences. However, it is known that automatic multiple sequenceExpand
  • 1,414
  • 114
The Jpred 3 secondary structure prediction server
Jpred (http://www.compbio.dundee.ac.uk/jpred) is a secondary structure prediction server powered by the Jnet algorithm. Jpred performs over 1000 predictions per week for users in more than 50Expand
  • 1,495
  • 89
  • Open Access
Evaluation and improvement of multiple sequence methods for protein secondary structure prediction
A new dataset of 396 protein domains is developed and used to evaluate the performance of the protein secondary structure prediction algorithms DSC, PHD, NNSSP, and PREDATOR. The maximum theoreticalExpand
  • 622
  • 86
  • Open Access
Application of multiple sequence alignment profiles to improve protein secondary structure prediction
The effect of training a neural network secondary structure prediction algorithm with different types of multiple sequence alignment profiles derived from the same sequences, is shown to provide aExpand
  • 794
  • 55
  • Open Access
Identification of multiple distinct Snf2 subfamilies with conserved structural motifs
The Snf2 family of helicase-related proteins includes the catalytic subunits of ATP-dependent chromatin remodelling complexes found in all eukaryotes. These act to regulate the structure and dynamicExpand
  • 554
  • 48
  • Open Access
Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis
We describe the genome sequence of the protist Trichomonas vaginalis, a sexually transmitted human pathogen. Repeats and transposable elements comprise about two-thirds of the ∼160-megabase genome,Expand
  • 667
  • 41
  • Open Access
System-Wide Changes to SUMO Modifications in Response to Heat Shock
The small ubiquitin-like modifier protein SUMO is redistributed among many targets to mediate both short- and long-term signaling events. SUMO Status Revealed Posttranslational modification ofExpand
  • 411
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  • Open Access
ALSCRIPT: a tool to format multiple sequence alignments.
  • G. Barton
  • Biology, Medicine
  • Protein engineering
  • 1993
The ALSCRIPT program described in this article was developed specifically to allow the easy formatting and graphical display of large multiple alignments. Although written originally for the author'sExpand
  • 1,056
  • 28
  • Open Access
JPred: a consensus secondary structure prediction server
UNLABELLED An interactive protein secondary structure prediction Internet server is presented. The server allows a single sequence or multiple alignment to be submitted, and returns predictions fromExpand
  • 1,006
  • 28
  • Open Access