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Neuromodulation of the locomotor network by dopamine in the isolated spinal cord of newborn rat
We have analysed the action of the neuromodulatory catecholamine, dopamine (DA), on the lumbar locomotor network using an isolated in vitro newborn rat spinal cord preparation. We have also attemptedExpand
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Prominent Role of the Spinal Central Pattern Generator in the Recovery of Locomotion after Partial Spinal Cord Injuries
The re-expression of hindlimb locomotion after complete spinal cord injuries (SCIs) is caused by the presence of a spinal central pattern generator (CPG) for locomotion. After partial SCI, however,Expand
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Neuroanatomical Study of the A11 Diencephalospinal Pathway in the Non-Human Primate
Background The A11 diencephalospinal pathway is crucial for sensorimotor integration and pain control at the spinal cord level. When disrupted, it is thought to be involved in numerous painfulExpand
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Noradrenergic Modulation of Intrinsic and Synaptic Properties of Lumbar Motoneurons in the Neonatal Rat Spinal Cord
Although it is known that noradrenaline (NA) powerfully controls spinal motor networks, few data are available regarding the noradrenergic (NAergic) modulation of intrinsic and synaptic properties ofExpand
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Plasticity of locomotor sensorimotor interactions after peripheral and/or spinal lesions
The present paper reviews aspects of locomotor sensorimotor interactions by focussing on work performed in spinal cats. We provide a brief overview of spinal locomotion and describe the effects ofExpand
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Interplay between neuromodulator‐induced switching of short‐term plasticity at sensorimotor synapses in the neonatal rat spinal cord
In the present study, we investigated the modulation of short‐term depression (STD) at synapses between sensory afferents and rat motoneurons by serotonin, dopamine and noradrenaline. STD wasExpand
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Age-Related Changes in Pre- and Postsynaptic Partners of the Cholinergic C-Boutons in Wild-Type and SOD1G93A Lumbar Motoneurons
Large cholinergic synaptic terminals known as C-boutons densely innervate the soma and proximal dendrites of motoneurons that are prone to neurodegeneration in amyotrophic lateral sclerosis (ALS).Expand
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Multiple Mechanisms for Integrating Proprioceptive Inputs That Converge on the Same Motor Pattern-Generating Network
Movement-derived sensory feedback adapts centrally generated motor programs to changing behavioral demands. Motor circuit output may also be shaped by distinct proprioceptive systems with differentExpand
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Re-expression of locomotor function after partial spinal cord injury.
After a complete spinal section, quadruped mammals (cats, rats, and mice) can generally regain hindlimb locomotion on a treadmill because the spinal cord below the lesion can express locomotionExpand
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Dual spinal lesion paradigm in the cat: evolution of the kinematic locomotor pattern.
The recovery of voluntary quadrupedal locomotion after an incomplete spinal cord injury can involve different levels of the CNS, including the spinal locomotor circuitry. The latter conclusion wasExpand
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