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Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample.
OBJECTIVE Autism spectrum disorders are now recognized to occur in up to 1% of the population and to be a major public health concern because of their early onset, lifelong persistence, and highExpand
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Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP)
BACKGROUND Recent reports have suggested that the prevalence of autism and related spectrum disorders (ASDs) is substantially higher than previously recognised. We sought to quantify prevalence ofExpand
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Functional impact of global rare copy number variation in autism spectrum disorders
The autism spectrum disorders (ASDs) are a group of conditions characterized by impairments in reciprocal social interaction and communication, and the presence of restricted and repetitiveExpand
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Infants with autism: an investigation of empathy, pretend play, joint attention, and imitation.
Systematic studies of infants with autism have not been previously carried out. Taking advantage of a new prospective screening instrument for autism in infancy (S. Baron-Cohen et al., 1996), theExpand
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Mapping autism risk loci using genetic linkage and chromosomal rearrangements
Autism spectrum disorders (ASDs) are common, heritable neurodevelopmental conditions. The genetic architecture of ASDs is complex, requiring large samples to overcome heterogeneity. Here we broadenExpand
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Impairment in movement skills of children with autistic spectrum disorders
Aim  We undertook this study to explore the degree of impairment in movement skills in children with autistic spectrum disorders (ASD) and a wide IQ range.
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Psychological markers in the detection of autism in infancy in a large population.
BACKGROUND Investigation to see if there are key psychological risk indicators for autism in a random population study of children at 18 months of age; and to assess how well these discriminateExpand
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A screening instrument for autism at 18 months of age: a 6-year follow-up study.
OBJECTIVES A population of 16,235 children aged 18 months was screened using the Checklist for Autism in Toddlers (CHAT) to identify childhood autism (CA). Two further screening procedures wereExpand
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Autism spectrum disorders at 20 and 42 months of age: stability of clinical and ADI-R diagnosis.
The association between, and stability of, clinical diagnosis and diagnosis derived from the Autism Diagnostic Interview-Revised (ADI-R; Lord, Rutter, & Le Couteur, 1994) was examined in a sample ofExpand
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Testing joint attention, imitation, and play as infancy precursors to language and theory of mind
Abstract Various theoretical accounts propose that an important developmental relation exists between joint attention, play, and imitation abilities, and later theory of mind ability. However, veryExpand
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