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Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis.
- J. Lasky, L. Ortiz, +6 authors M. Friedman
- Biology, Medicine
- American journal of physiology. Lung cellular and…
- 1 August 1998
Connective tissue growth factor (CTGF) is a newly described 38-kDa peptide mitogen for fibroblasts and a promoter of connective tissue deposition in the skin. The CTGF gene promotor contains a… Expand
Improved protein extraction and protein identification from archival formalin-fixed paraffin-embedded human aortas.
- Zongming Fu, K. Yan, +8 authors J. V. Van Eyk
- Biology, Medicine
- Proteomics. Clinical applications
- 1 April 2013
PURPOSE Evaluate combination of heat and elevated pressure to enhance protein extraction and quality of formalin-fixed (FF), and FF paraffin-embedded (FFPE) aorta for proteomics. EXPERIMENT DESIGN… Expand
The effect of proteolytic enzymes on the α9-nicotinic receptor-mediated response in isolated frog vestibular hair cells
- J. C. Holt, M. Lioudyno, G. Athas, M. Garcia, P. Guth
- Medicine, Chemistry
- Hearing Research
- 1 February 2001
In frog vestibular organs, efferent neurons exclusively innervate type II hair cells. Acetylcholine, the predominant efferent transmitter, acting on acetylcholine receptors of these hair cells… Expand
The metabotropic glutamate receptors of the vestibular organs
This research sought to test the presence and function of metabotropic excitatory amino acid receptors (mGluR) in the frog semicircular canal (SCC). The mGluR agonist +/-… Expand
Retroviral determinants of leukemogenesis.
The slowly transforming, leukemogenic retroviruses of humans and other mammals induce malignant disease after prolonged latency but lack an oncogene to which their malignant potential can be… Expand
Genetic determinants of feline leukemia virus-induced multicentric lymphomas.
Three discrete forms of feline leukemia virus (FeLV)-associated lymphoma have been described clinically: (1) thymic, (2) alimentary, and (3) multicentric. The most common and best-characterized… Expand
A role for chloride in the hyperpolarizing effect of acetylcholine in isolated frog vestibular hair cells
Acetylcholine (ACh) is the dominant transmitter released from inner ear efferent neurons. In frog vestibular organs, these efferent neurons synapse exclusively with type II hair cells. Hair cells… Expand
Emphysematous lesions, inflammation, and fibrosis in the lungs of transgenic mice overexpressing platelet-derived growth factor.
Because of its expression pattern and its potent effects on mesenchymal cells, platelet-derived growth factor (PDGF) has been implicated as an important factor in epithelial-mesenchymal cell… Expand
Function of a unique sequence motif in the long terminal repeat of feline leukemia virus isolated from an unusual set of naturally occurring tumors.
Feline leukemia virus (FeLV) proviruses have been characterized from naturally occurring non-B-cell, non-T-cell tumors occurring in the spleens of infected cats. These proviruses exhibit a unique… Expand
The USH1C 216G→A splice-site mutation results in a 35-base-pair deletion
- Jennifer Lentz, S. Savas, San-San Ng, G. Athas, P. Deininger, B. Keats
- Medicine, Biology
- Human Genetics
- 1 February 2005
Usher syndrome is characterized by profound hearing loss and retinal degeneration. A splice-site mutation, 216G→A, in exon 3 of USH1C is associated with Acadian Usher type IC. This mutation was… Expand