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Architecture of the Yeast Cell Wall
In a previous study (Kollár, R., Petráková, E., Ashwell, G., Robbins, P. W., and Cabib, E. (1995) J. Biol. Chem. 270, 1170–1178), the linkage region between chitin and β(1→3)-glucan wasExpand
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Receptor-mediated endocytosis of transferrin in K562 cells.
Human diferric transferrin binds to the surface of K562 cells, a human leukemic cell line. There are about 1.6 X 10(5) binding sites per cell surface, exhibiting a KD of about 10(-9) M. Upon warmingExpand
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Binding of apotransferrin to K562 cells: explanation of the transferrin cycle.
The binding of apotransferrin to the transferrin receptor on the surface of human leukemic K562 cells was found to be significantly less tight than that of the holoprotein, diferric transferrin. TheExpand
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Alginic acid metabolism in bacteria. I. Enzymatic formation of unsaturated oligosac-charides and 4-deoxy-L-erythro-5-hexoseulose uronic acid.
Alginic acid, a high molecular weight linear polymer obtained from seaweed, is widely used as an added product to food due to its property of forming highly viscous solutions. Originally described asExpand
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Architecture of the yeast cell wall. The linkage between chitin and beta(1-->3)-glucan.
To isolate the putative linkage region between chitin and beta(1-->3)-glucan, Saccharomyces cerevisiae cell walls were digested with beta(1-->3)-endoglucanase and the reducing ends of theExpand
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Physical and chemical studies on ceruloplasmin. V. Metabolic studies on sialic acid-free ceruloplasmin in vivo.
Abstract Injection into rabbits of radioactive ceruloplasmin from which sialic acid had been removed enzymatically resulted in a rapid disappearance of the asialoceruloplasmin from the serum and itsExpand
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The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins.
  • G. Ashwell, A. Morell
  • Chemistry, Medicine
  • Advances in enzymology and related areas of…
  • 22 November 2006
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The role of sialic acid in determining the survival of glycoproteins in the circulation.
Abstract Evidence is presented to indicate a generalized role for the terminal sialic acid residues of circulating glycoproteins. Upon injection into rats, all of the desialylated plasma proteinsExpand
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The isolation and properties of a rabbit liver binding protein specific for asialoglycoproteins.
Abstract The ability of hepatic plasma membranes to bind desialylated glycoproteins as a prelude to transport and catabolism has been reported earlier. The present study describes the purification,Expand
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