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Early and midterm outcome after off-pump and on-pump surgery in Beating Heart Against Cardioplegic Arrest Studies (BHACAS 1 and 2): a pooled analysis of two randomised controlled trials
TLDR
Off-pump coronary surgery significantly lowers in-hospital morbidity without compromising outcome in the first 1-3 years after surgery compared with conventional on-p pump coronary surgery. Expand
Inflammatory response after coronary revascularization with or without cardiopulmonary bypass.
TLDR
CABG on the beating heart is associated with a significant reduction in inflammatory response and postoperative infection when compared with conventional revascularization with CPB and cardioplegic arrest. Expand
Human Adult Vena Saphena Contains Perivascular Progenitor Cells Endowed With Clonogenic and Proangiogenic Potential
TLDR
SVPs generated from human vein CD34-positive/CD31-negative progenitor cells might represent a new therapeutic tool for angiogenic therapy in ischemic patients. Expand
Randomized comparison of percutaneous coronary intervention with coronary artery bypass grafting in diabetic patients. 1-year results of the CARDia (Coronary Artery Revascularization in Diabetes)
TLDR
The CARDia trial did show that multivessel PCI is feasible in patients with diabetes, but longer-term follow-up and data from other trials will be needed to provide a more precise comparison of the efficacy of these 2 revascularization strategies. Expand
Effect of body mass index on early outcomes in patients undergoing coronary artery bypass surgery.
TLDR
Obesity does not affect the risk of perioperative death and other adverse outcomes compared to normal weight, yet obese patients appear less likely to be selected for surgery than normal weight patients. Expand
Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery.
TLDR
Red blood cell transfusion in patients having cardiac surgery is strongly associated with both infection and ischemic postoperative morbidity, hospital stay, increased early and late mortality, and hospital costs. Expand
On-pump versus off-pump coronary revascularization: evaluation of renal function.
TLDR
It is suggested that off pump coronary revascularization offers a superior renal protection when compared with conventional coronary Revascularization with cardiopulmonary bypass and cardioplegic arrest in first time coronary bypass patients. Expand
Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and cyclic AMP levels in the rabbit corpus cavernosum in vitro.
TLDR
Sildenafil specifically increases cGMP levels in rabbit corpora cavernosa; the increase is greater in the presence of SNP indicating that, in vivo, sildanafil may enhance erection by the augmentation of nitric oxide-mediated relaxation pathways. Expand
Beating versus arrested heart revascularization: evaluation of myocardial function in a prospective randomized study.
TLDR
The results suggest that off pump coronary revascularization is a safe and effective strategy for myocardial revascularizations. Expand
Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition.
TLDR
Diminishing oxidative stress may protect the heart against ischaemia-reperfusion injury by preventing opening of the mitochondrial permeability transition (MPT) pore by propofol, a useful adjunct to cardioplegic solutions in heart surgery. Expand
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