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Different Patterns of White Matter Degeneration Using Multiple Diffusion Indices and Volumetric Data in Mild Cognitive Impairment and Alzheimer Patients
The current results suggest that a combination of secondary and primary degeneration occurrs in MCI and AD, although the secondary degeneration appears to have a more critical role during the stages of disease involving dementia. Expand
Religious coping and its influence on psychological distress, medication adherence, and quality of life in inflammatory bowel disease.
Religious coping is significantly associated with psychological distress, HRQoL, and adherence in IBD. Expand
Autobiographical Memory Disturbances in Depression: A Novel Therapeutic Target?
It is proposed that the manipulation of the reconsolidation of autobiographical memories in depression might represent a novel yet largely unexplored, domain-specific, therapeutic opportunity for depression treatment. Expand
Association between white matter fiber integrity and subclinical psychotic symptoms in schizophrenia patients and unaffected relatives
The results suggest that clinical and subclinical presentations of psychotic symptoms are associated with aberrant integrity of multiple WM tracts, and this association may represent an endophenotype of schizophrenia, since it is present in unaffected relatives as well. Expand
Cognitive and behavioural effects of physical exercise in psychiatric patients
The current review outlines the under-appreciated effects of physical exercise on the course of psychiatric disorders, focussing on recent findings from animal and human research. Several studiesExpand
Cognitive dysfunction in depression - pathophysiology and novel targets.
It is found that reciprocal and overlapping biological pathways may contribute to cognitive dysfunction in MDD, including an hyperactive hypothalamic-pituitary-adrenal axis, an increase in oxidative and nitrosative stress, inflammation, mitochondrial dysfunction, increased apoptosis as well as a diminished neurotrophic support. Expand
Frontal white matter alterations are associated with executive cognitive function in euthymic bipolar patients.
The results indicate a direct link between executive cognitive functioning and abnormal WM microstructural integrity of fronto-limbic tracts in remitted BD patients, and add evidence to the neuronal disruption that underlies the residual symptomatology of BD. Expand
Multimodal assessments of the hippocampal formation in schizophrenia and bipolar disorder: Evidences from neurobehavioral measures and functional and structural MRI
The results of this study suggest a graded expression of verbal learning deficits accompanied by structural alterations within the hippocampus in BD patients and Sz patients, with SZ patients being more strongly affected. Expand
Cognitive disconnective syndrome by single strategic strokes in vascular dementia
Vascular strategic syndromes connote the predominantly impaired cognitive/behavioral symptom of each site, and subcortical strategic strokes that express similar cognitive/ behavioral elements, by sharing common pathways are analysed. Expand
Association of microstructural white matter abnormalities with cognitive dysfunction in geriatric patients with major depression
Fractional anisotropy (FA) as a measure of WM integrity was investigated in elderly MDD subjects in comparison with 18 age-matched controls using tract-based spatial statistics (TBSS) and correlated with clinical and cognitive parameters and suggested that cognitive deficits are related to the loss of integrity in WM tracts associated with the disorder. Expand