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Summary of the recommendations on sexual dysfunctions in men.
TLDR
Specific evaluation, treatment guidelines, and algorithms were developed for every sexual dysfunction in men, including erectile dysfunction; disorders of libido, orgasm, and ejaculation; Peyronie's disease; and priapism. Expand
Pharmacotherapy for Erectile Dysfunction: Recommendations From the Fourth International Consultation for Sexual Medicine (ICSM 2015).
TLDR
PDE5 inhibitors remain a first-line treatment option because of their excellent efficacy and safety profile and intraurethral and topical alprostadil provide an alternative, less invasive treatment option. Expand
Relationship between QaT and RR intervals in rats, guinea pigs, rabbits, and primates.
TLDR
Over a wide range of heart rates the authors tested various formulas for their value in correcting for the variation in QT interval associated with changes in heart rate, finding little difference between the various formulas in their ability to increase the precision of QaTc and the normality of its distribution. Expand
Initial characterization of hydrogen sulfide effects in female sexual function.
TLDR
These pilot studies clearly indicate the smooth muscle relaxant effect of H(2)S in female genital tract, mediating through cyclic adenosine 3':5'-monophosphate, nitric oxide-cyclic guanosine monoph phosphate and K(+)(ATP) channels. Expand
The effect of propofol on human gastric and colonic muscle contractions.
TLDR
It is found that, at clinically relevant concentrations, propofol impaired gastrointestinal contractile activity and the success of enteral feeding requires a normal gastrointestinal motility. Expand
The effect of oxytocics stored at high temperatures on postpartum uterine activity
TLDR
The clinical efficacy of Methergin@ and Syntocinon@ in the third stage of labour when stored at three different temperatures over a period is evaluated. Expand
Effect of prostaglandins A1, A2, B1, B2, E2 and F2α on human umbilical cord vessels
TLDR
This is the first report of the constrictor effect of PGA and PGB compounds and these naturally occuring prostaglandins with high potencies may play a role in spontaneous closure of umbilical vessels. Expand
ORIGINAL RESEARCH—PHOSPHODIESTERASE INHIBITOR THERAPY FOR ED: Pharmacotherapy for Erectile Dysfunction
TLDR
The recommendations concerning state-of-the-art knowledge in the respective sexual medicine topic represent the opinion of experts from five continents developed in a process over a two-year period. Expand
Antiarrhythmic actions of tedisamil: Studies in rats and primates
TLDR
Findings are consistent with the hypothesis that tedisamil increased refractoriness, which resulted in extended path lengths for reentry circuits and slower rates during episodes of ventricular tachycardia, and with the lack of significant sodium-channel blockade. Expand
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