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The influence of solvent molecules on NMR spectrum of barbituric acid in the DMSO solution
This work shows the modification of barbituric acid (BA) chemical shifts by dimethylsulphoxide (DMSO) molecules. The discussed changes are caused by creation of the H-bonded associates formed by…
Cyclic sulfates as useful tools in the asymmetric synthesis of 1-aminocyclopropane-1-carboxylic acid derivatives
Synthesis, spectroscopy, and theoretical calculations of some 2-thiohydantoin derivatives as possible new fungicides
- Katarzyna Kobyłka, G. Żuchowski, W. Tejchman, K. Zborowski
- ChemistryJournal of Molecular Modeling
- 24 August 2019
It was documented that both the studied compounds exist predominantly in the tautomeric structure, in which the movable hydrogen is connected to the nitrogen atom in the hydantoin ring, whereas the other one exists as a mixture of two geometric isomers.
Discovery of Cinnamylidene Derivative of Rhodanine with High Anthelmintic Activity against Rhabditis sp.
A series of 16 cinnamylidene derivatives of rhodanine, including newly synthesized methoxy derivatives and previously obtained chloro, nitro, and diethylamine derivatives, was investigated towards anthelmintic activity and it is concluded that the tested compound 2 can be further investigated as a potential anthel mintic drug.
Influence of substitution of oxygen by sulfur on maltol properties
Replacing oxygen by sulfur in a maltol molecule generates a family of new very interesting ligands: thiohydroxypyrones. In this work, theoretical calculations have been performed for all possible…
A molecular modelling explanation of the unexpected stereochemistry observed in the alkylation of oxazinone-derived glycine equivalents using 4-chloromethyl-1,3,2-dioxathiolane-2-oxide
Modeling of stability and properties of anionic and cationic tautomers of the 3-hydroxypyridin-4-one system
Enantioselective chromatography of alkyl derivatives of 5-ethyl-5-phenyl-2-thiobarbituric acid studied by semiempirical AM1 method.
The ability of beta-cyclodextrin to act as a mobile phase additive in reversed-phase HPLC to separate enantiomers by liquid chromatography and rationalize their order of elution is confirmed.
Hydrolysis of 2,4-dithiophenobarbital.
- Monika Tarsa, G. Żuchowski, A. Stasiewicz-Urban, J. Bojarşki
- ChemistryActa poloniae pharmaceutica
- 1 March 2009
Hydrolysis of 2,4-dithiophenobarbital in aqueous solutions of pH 2-12 was investigated using UV spectrophotometry and the preliminary estimation of degradation products was accomplished using thin layer chromatography.