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Small nucleolar RNAs (snoRNAs) play a key role in ribosomal RNA (rRNA) biogenesis. Box C/D snoRNAs guide the site-specific 2'-O-ribose methylation of nucleotides in rRNAs and small nuclear RNAs (snRNAs). A number of box C/D snoRNAs and their fragments have recently been reported to regulate post-transcriptional modifications and the alternative splicing of(More)
Complete surgical deafferentation of the medio-basal hypothalamus (MBH) in rats entails suppression of the oestrus cycle as well as a decrease of luteinizing hormone, estrogens and progesterone release into the blood due to a sharp fall of the luliberine content in the median eminence and arquate nuclei. No connection was revealed between the character of(More)
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