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A weighting restriction with frequency components is proposed for the insulin delivery on Type 1 Diabetics Mellitus (T1DM) towards the control of the blood glucose level. The weighting restriction is stated from a model of healthy subjects which includes a rate for insulin delivery. The frequency components are incorporated via a transfer function from the(More)
Wastewater treatment is a current technological and scientific challenge due to the requirements of the high variety of wastewater coming from industries and municipal residuals. In particular, anaerobic digestion process is a useful approach for treatment of wastewater with high load of organic matter. The need of implementing treatment plants for(More)
Body nitrogen retention is dependent on the amount of dietary protein consumed, as well as the fat and carbohydrate content in the diet, due to the modulation of amino acid oxidation. PPARα is a transcription factor involved in the upregulation of the expression of enzymes of fatty acid oxidation. However, the role of putative PPARα response elements(More)
Urocortin 1, highly conserved metazoan gene of the corticotropin-releasing hormone family, is a simple gene structured in two exons and the corresponding intron. The urocortin 1 prepropeptide is entirely coded in the second exon. Preliminary non-isotopic in situ hybridization experiments with an oligonucleotide complementary to an intron sequence of the(More)
This paper presents the application of a recurrent multilayer perceptron neural network for modeling blood glucose dynamics in Type 1 Diabetes Mellitus (T1DM). Training is performed based on an extended Kalman filtering (EKF) learning algorithm. Then, the EKF performance is compared with the well-known Levenberg-Marquardt (LM) learning algorithm. The goal(More)
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