G. Prem Kumar

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Enrofloxacin is a fluoroquinolone derivative used for treating urinary tract, respiratory and skin infections in animals. However, low solubility and low bioavailability prevented it from using on humans. Polyvinylpyrrolidone (PVP) is an inert, non toxic polymer with excellent hydrophilic properties, besides it can enhance bioavailability by forming drug(More)
Performance degradation in communication networks can be viewed to be caused by a set of faults, called soft failures, owing to which the network resources like bandwidth can not be utilized to the expected level. An automated solution to the performance management problem involves identifying these soft failures and use/suggest suitable remedies to tune(More)
a fault tolerant reversible logic has gained Importance as they consume low power and less heat Dissipation. The benefits of logical reversibility can be gained only after employing physical reversibility. Every future Technology will have to use reversible gates in order to reduce Power. In this paper, a new fault tolerant reversible 4*4 RR-gate which(More)
In this paper, a method is proposed for network restoration using a centralized, static restoration after failure, where the restoration initiated at the local node or at the source using a hybrid strategy. The traditional approaches to network (re)routing are based on the heuristics that are prone to enter local minima. A new rerouting algorithm is(More)
6-Mercaptopurine is a cytotoxic and immunosuppressant drug. The use of this drug is limited due to its poor bioavailability and short plasma half-life. In order to nullify these drawbacks, 6-mercaptopurine-chitosan nanoparticles (6-MP-CNPs) were prepared and evaluated to study the influence of preparation conditions on the physicochemical properties by(More)
A Big Bang-Big Crunch Optimization Algorithm (BBBCOA) is availed in the design of PID controller. A sixth order system is reckoned and is scaled down to second order with the help of BB-BCOA, Particle Swarm Optimization(PSO), Genetic Algorithm (GA) Hankel Norm Approximation (HNA). Later, a controller is designed by approximate model matching technique in(More)
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