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The effects of age on calciotropic hormones are not completely understood. The presence of secondary hyperparathyroidism has previously been demonstrated, particularly in patients with hip fracture. The role of a disturbance of vitamin D metabolism, especially a defect in lα-hydroxylation, is debated. The aim of this study was to compare serum parathyroid(More)
Proximal femur fractures in elderly people are more and more frequent. Falls and senile bone disorders are the risk factors of this fracture. In order to understand the mechanisms of these bone disorders, we studied 21 consecutive patients with this fracture using bone histomorphometry. Measurements of serum intact parathormone (PTH), 25-(OH)-vitamin D,(More)
A radioimmunoassay (RIA) of chicken growth hormone (c-GH) has been developed using growth hormone produced by recombinant DNA technology. The best rabbit antiserum was used at 1/300,000 final dilution. Hormone labelling by iodine-125, achieved by chloramine T, allowed a specific activity of 3.7 MBq/micrograms. The equilibrium curves show that optimal(More)
Electromyographic (EMG) activity of the uterus was recorded in vivo in 4 conscious ovariectomized ewes treated with oestrogen (one injection of 100 micrograms of oestradiol benzoate). Doses of 500 micrograms of purified porcine relaxin were injected intravenously 12, 16, 20, 24, 28 and 32 hrs after oestrogen treatment. Relaxin had an inhibitory effect on(More)
In the first part: the charcoal-assay method was briefly described (sensitivity: PR = 10 fmol/mg protein, ER = 5 fmol/mg protein), and criteria for the validity of this method were analysed: sufficient amount of tumor (150-200 mg) minimum protein concentration should be 2 mg/ml choice of a suitable labeled hormone plotting of Scatchard curve with at least 4(More)
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