G. Pessina

Learn More
Intracellular Ca(2+) mobilization and release into mammal CSF plays a fundamental role in the etiogenesis of fever induced by the proinflammatory cytokine interleukin-1beta (IL-1beta) and other pyrogens. The source and mechanism of IL-1beta-induced intracellular Ca(2+) mobilization was investigated using two experimental models. IL-1beta (10 ng/ml)(More)
To elucidate the mechanism of cell growth regulation by nitric oxide (NO) and the role played in it by Ca2+, we studied the relationship among intracellular Ca2+ concentration ([Ca2+]i), mitogen-activated protein kinases [extracellular signal-regulated protein kinase (ERK)] and proliferation in cell lines exposed to different levels of NO. Data showed that(More)
CUORE is a proposed tightly packed array of 1000 T eO 2 bolometers, each being a cube 5 cm on a side with a mass of 760 g. The array consists of 25 vertical towers , arranged in a square of 5 towers by 5 towers, each containing 10 layers of 4 crystals. The design of the detector is optimized for ultralow-background searches: for neutrinoless double beta(More)
We report the final result of the CUORICINO experiment. Operated between 2003 and 2008, with a total exposure of 19.75 kg. y of 130 Te, CUORICINO was able to set a lower bound on the 130 Te 0mbb half-life of 2.8 x 10 24 years at 90% C.L. The limit here reported includes the effects of systematic uncertainties that are examined in detail in the paper. The(More)
Measurement of ψ(2S) meson production in pp collisions at √ s = 7 TeV Abstract The differential cross-section for the inclusive production of ψ(2S) mesons in pp collisions at √ s = 7 TeV has been measured with the LHCb detector. The data sample corresponds to an integrated luminosity of 36 pb −1. The ψ(2S) mesons are reconstructed in the decay channels(More)
Nerve cells are very responsive to weak pulsed electromagnetic fields (EMFs). Such non-ionizing radiation, with frequencies of 0-300 Hz and 0.1-100 mT, can affect several cellular activities, with unusual dose-response characteristics. The present study examined the effect of a 2-h exposure of synaptosomes on a system generating a peak magnetic field of 2(More)
The CUORE (Cryogenic Underground Observatory for Rare Events) experiment projects to construct and operate an array of 1000 cryogenic thermal detectors of TeO 2 , of a mass of 760 g each, to investigate rare events physics, in particular, double beta decay and non baryonic particle dark matter. A first step towards CUORE is CUORICINO, an array of 62 of(More)
Using pp collision data corresponding to an integrated luminosity of 1.0 fb(-1) and collected by LHCb in 2011 at a center-of-mass energy of 7 TeV, we report the measurement of direct CP violation in B(s)(0)→K(-)π(+) decays, A(CP)(B(s)(0)→K(-)π(+)=0.27±0.04 (stat)±0.01 (syst), with significance exceeding 5 standard deviations. This is the first observation(More)
Some biological parameters before and after an acute episode of cigarette smoking in rats have been evaluated. The carboxyhaemoglobin levels depended either on the number of cigarettes, or on the time of exposure to cigarette smoke and returned to pre-smoking values in about 2 h. The evaluation of the kinetics of alveolar and peritoneal macrophages in rats(More)
Some biological effects of chronic cigarette smoking (two cigarettes for 2 h, daily for 4 months) in rats were evaluated. During the smoking period, body weight of smoker rats was always significantly lower than that of control rats. Immediately after the last smoking session the carboxyhaemoglobin concentration in the blood was about 8.5% and the(More)