G. P. Elizarova

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A comparative analysis of immunological properties of previously isolated and structurally characterized glycosylated porcine prolactin was performed. Immunoelectrophoresis with antisera to nonmodified and glycolysated hormones revealed no qualitative differences in their immunological properties. Two radioimmunoassay systems for glycosylated and(More)
In the primary structure of bovine prolactin a hydrophobic fragment 79-88 of the peptide chain was found, which participated in a maintenance of conformation of the hormone molecule in a solution due to hydrophobic interactions. The fragment contained about 50% of leucine residues, which are currently considered as important in determination of(More)
The effect of monomeric (glycosylated and unglycosylated) and dimeric form of porcine prolactin on change of the blood levels of triglycerides (TG) and cholesterol in lipoproteins (LP) of different density and the activity of the main enzymes of plasmatic and liver lipid metabolism were studied under the conditions of experimental hyperprolactinemia in(More)
The corticotropins from two species of whales, e. g. seiwhale (Balaenoptera borealis) and finwhale (Balaenoptera physalus) were subjected to hydrolysis by trypsin, chymotrypsin and pepsin. The peptide fragments were separated by gel-filtration through Sephadex and partition paper chromatography. The study of the amino acid sequence of the peptides obtained(More)
Some features of the morphological cellular structure of prolactin secreting human pituitary adenomas and their secretion of prolactin and somatotropic hormone in primary suspension cultures were investigated. A possiblein vitro proliferation of lactotrophs was established. The inhibitory effect of somatostatin and its synthetic analog sandostatin, on(More)
To investigate how growth hormone (GH)-releasing peptide (GHRP) and GH-releasing hormone (GHRH) interact in patients with short stature, we examined the acute effects of GHRH1-29NH2, GHRP-2, and the combination of GHRH1-29NH2 and GHRP-2 on GH release in children with GH insufficiency ([GHI] group A) and idiopathic short stature ([ISS] group B). Ten children(More)