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Nicotinic acetylcholine receptor protein has been purified from foetal and adult skeletal muscle by extraction in non-ionic detergent followed by purification on immobilised α-toxin. Purified foetal and adult receptors focused as single, sharp peaks whether directly labelled with (125)I or indirectly labelled with (125)I-α-bungarotoxin. Polyacrylamide gel(More)
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