G L Bekaia

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It is known that in the process of gestation and delivery, jointly with well recognized regulatory factors such as sex steroids, catecholamines, oxytocin and prostaglandins the substances of peptidergic nature are also involved. One of these substances is a Calcitonin Gene-Related Peptide (CGRP). In experiments on groups of pregnant and non pregnant rats we(More)
Along with the brief history of amide local anesthetics development, their most important properties (from the viewpoint of use in clinical dental practice), are also reviewed. In particular, some properties of most commonly used local anesthetics, such as lidocaine, mepivacaine, prilocaine, bupivacaine and articaine are analysed. The most important data(More)
Existence of the autoregulation phenomenon in the blood supply system of the optic nerve has been established in the 1990; however, some of its quantitative and qualitative characteristics still require clarification. The goal of the present work was assessment of the lower margin in autoregulation of the blood supply of the optic nerve in the rabbit in(More)
Experimental studies on rats revealed that the newborns growth retardation, caused by long-term treatment with Dexamethasone in the neonatal period, can be prevented by the simultaneous with dexamethasone administration of the nitric oxide donor--L-arginine. This indicates that the mentioned Dexamethasone-induced growth disorder is caused by inhibition of(More)
It is believed that hyperemia in the skin, resulting from applied weak mechanical pressure delays the development of ischemia, and that it is a defensive neurovascular reaction against the local pressure, which can be considered as a critical point in terms of prevention of ischemia and, respectively, the risk for development of bedsores. Taking into(More)
Neruronal activity evoked by pain impulsation in the specific thalamic nuclei and sensorimotor cortex has been recorded in cat. The following data were obtained. Evoked nociceptive neuronal activity was inhibited by stimulation of the nonspecific thalamic nuclei. An antinociceptive impact of the nonspecific thalamic nuclei on the specific thalamic units was(More)
Despite the fact that the side effects of prolonged treatment with dexamethasone are well known, information about its effects on the central nervous system is very limited. Experimental study of long-term effects of dexamethasone administration in the neonatal period on behavioral activity of rats in the open field was conducted. Four groups of newborn(More)
Evoked responses of the motor cortex (dendritic and slow negative potentials) elicited by its direct electrical stimulation, primary, nonspecific and antidromic responses elicited by stimulation of ventrolateral and intralaminar thalamic nuclei and pyramidal pathways and the respective postsynaptic responses of neurons were studied in acute experiments on(More)
In a review article the authors based on the analysis of the literature, conclude that the Calcitonin Gene-Related Peptide (CGRP) inhibits myometrial contractility at the background of the nonselective Nitric Oxide Synthase inhibitor (L-NAME) action. Along with this, there are evidences that in NOS-deficient rats the process of pregnancy proceeds normally.(More)
Spontaneous electrical activity of the cerebellar cortex and fastigial nuclei was studied in unrestrained cats with implanted electrodes. Rhythmic (4-8/s) electrical activity was recorded in the fastigial nuclei of the cerebellum in paradoxical sleep as well as during some fragments of active wakefulness. A weak correlation between these processes was(More)