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The role of extracellular K+ concentration in the propagation velocity of action potential was tested in isolated rat skeletal muscles. Different K+ concentrations were produced by KCl additions to extracellular solution. Action potentials were measured extracellularly by means of two annular platinum electrodes. Fibre bundles of m. soleus (SOL), m.(More)
Maximum twitch and tetanic tension development, time to peak, and half relaxation time were studied on isolated frog sartorius muscles stimulated directly in Ringer's solution at different temperatures. Cooling from 20 degrees C to 10 degrees C decreased the tetanic tension (Q10 = 1.3-1.4). At temperatures above 25 (30) degrees C the tension output was(More)
A study was made to reinvestigate the general validity of the force/endurance relation of isometric contractions. Relative force development, mean bioelectrical muscle activity and circulatory responses (blood pressure, interbeat interval) during isometric contractions of different muscle groups were compared. 6 men performed maximum isometric contractions(More)
The effect of a wide range of temperature on the development of twitch and tetanic tension was investigated in directly stimulated rat fast (EDL) and slow (SOL) twitch muscle preparations. When increasing the temperature from 6 to 30 degrees C the maximum tetanic tension rose steadily. The Q10 was 2.3 (EDL) and 2.7 (SOL) for temperatures between 12 and 22(More)
1. Na-octanoate (in Ringer's solution) affects the membrane resistance of isolated frog skeletal muscle fibres in a biphasic way. Initially there is an increase followed by a more slowly developing decrease. The effect depends on both the concentration of the fatty acid (1–20 mM) and the time of exposure (2–20 min). 2. In muscles exposed either to isotonic(More)
Octanol (1 mM) or octanoate (10 mM) almost totally depress the contraction amplitude of directly stimulated muscles in a few minutes. Octanoate in a concentration of 2 mM/l decreases the contraction amplitude by 20% and retards the caffeine contracture. The ratio between twitch and tetanus is affected by octanol only. The results suggest that octanol and(More)