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Abstract We have investigated the significance and mechanism of intraluminal pH effects on folate absorption in vivo and in vitro, with emphasis on patients with pancreatic insufficiency. Serum folic… (More)
Sulfasalazine (salicylazosulfapyridine), an agent widely used for the treatment of ileitis and colitis, is also a competitive inhibitor of intestinal folate transport (1, 2). The mechanism of action… (More)
Transitory renal failure occurred in a patient with acute intermittent porphyria in clinical remission following i.v. administration of 1 000 mg hematin. The clinical and biochemical picture… (More)
The present study was carried out in five cases of hepatic porphyria, including three of acute intermittent porphyria, one of variegate porphyria, and one of porphyria cutanea tarda in clinical… (More)
In a patient taking diphenylhydantoin, what looks like German measles could be the first evidence of a hepatotoxic reaction that is fatal in 40% of cases. In the case described, death occurred in a… (More)
Porphyrin and iron distributions in the liver biopsies of patients with Porphyria cutanea tarda (PCT) were investigated by comparison of composite photographs from fluorescence microscope and after… (More)