G . H . Spray

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The prevalence of anaemia and the occasional unexpected finding of low serum folic acid and vitamin-B12 concentrations in aged inpatients prompted this investigation. Anaemia, usually with normoblastic haemopoiesis, is common in the elderly (Bedford and Wollner, 1958; Lawson, 1960; Geill, 1962). Serum folic acid concentrations may be in the lower half of(More)
I . A semi-synthetic vitamin B,,-deficient diet, based on soya flour, is described. When supplemented with cydnocobalamin the diet appeared to be adequate for growth and reproduction in the rat. 2. Compared with their litter-mates on the supplemented diet, rats fed on the deficient diet from weaning showed reduced levels of vitamin Biz activity in the(More)