G. Goubeaud

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To evaluate their toxicity at the cellular level, middle molecules from uremic serum were incubated with erythrocytes from healthy subjects and the activity of the enzyme Delta-aminolevulinic acid dehydrase (D-ALA-D) and peroxidative hemolysis were investigated. Uremic middle molecules caused a significant decrease of the D-ALA-D activity of normal(More)
Possibility and necessity of the immunosuppressive treatment is considerably determined by the underlying pathologo-anatomical substrate. The uncertainty concerning the chances of the success of such a therapy for the individual patient at least still at present allows a latitude of estimation. From this results the demand for a particularly intensive(More)
A new dialysis method, termed hemodiafiltration, is proposed. The procedure consists of the combination of hemofiltration and conventional hemodialysis using high flux membranes with a transmembrane pressure (TMP) of 300--500 mmHg and a dialysate flow of 900 ml/min. Due to the combination of convective mass transfer and diffusion, the clearance values of(More)