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We consider the nonparametric estimation of the time to infection with HIV and the latency period between infection and the onset of AIDS in data where both the events of infection and AIDS are not directly observed. The methods use self-consistency equations that are more easily and quickly solvable than the nonparametric estimators proposed by De Gruttola(More)
The purpose of this paper is to develop a methodology to generate simplified models suitable for the analysis of the motion of a small particle, such as a spacecraft or an asteroid, in the Solar System. The procedure is based on applying refined Fourier analysis methods to the time–dependent functions that appear in the differential equations of the(More)
Most standards for the forthcoming beyond 3G (B3G) and 4G technologies state Orthogonal Frequency-Division Multiple Access (OFDMA) as a very promising candidate to be used as a digital modulation scheme. OFDMA combines multiple access techniques with Adap-tive Quadrature Amplitude Modulation (AQAM) to maximize system performance while keeping the errors(More)
Fabry´s disease is an X-linked recessive inborn error of metabolism of glycosphingolipids, caused by the deficiency of the lisosomal enzyme alpha-galactosidase. It is a rare disease with an estimated incidence rate of approximately 1:80.000 to 1:117,000 births in the general population. Recently, the growing knowledge about this disease has permitted the(More)
The problem of the estimation of the cumulative hazard function for time-to-tumour is considered for tumours that are not clinically observable and irreversible. The problem is posed in a compartmental model framework like that of Dewanji and Kalbfleisch (1986). The essential data from a single animal that are considered are: its group, age at death, mode(More)