G Giorgio Bombi

Learn More
Rat brain guanosine binding sites were studied by (i). a pharmacological approach to confirm the hypothesis of the existence of specific G-coupled receptors for guanosine (1) and, for the first time, delineate a structure-activity relationship for a series of guanosine derivatives; (ii). a molecular modelling approach to design a pseudo-receptor(More)
About ninety empirical functions for the representation of chromatographic peaks have been collected and tabulated. The table, based on almost 200 references, reports for every function: (1) the most used name; (2) the most convenient equation, with the existence intervals for the adjustable parameters and for the independent variable; (3) the applications;(More)
1. Extracellular guanosine has diverse effects on many cellular components of the central nervous system, some of which may be related to its uptake into cells and others to its ability to release adenine-based purines from cells. Yet other effects of extracellular guanosine are compatible with an action on G-protein linked cell membrane receptors. 2.(More)
In the 20 years, since the introduction of electrospray mass spectrometry (ESI-MS), the use of this technique in various fields of inorganic, organometallic, and analytical chemistry has been steadily increasing. In this study, the application of ESI-MS to the study of metal-ligand solution equilibria is reviewed (till 2004 included). In a first section,(More)
OBJECTIVES To evaluate the clinical aspects of hepatitis C virus (HCV) liver disease in anti-HCV+ve mothers, both during pregnancy and six months after delivery, and to assess the outcome of pregnancy. SETTING Obstetric department for high risk pregnancies of the University of Padova, Italy. PARTICIPANTS Seventeen hundred consecutive pregnant women were(More)
A recent paper by C. N. Martyn and colleagues (1) appears to reinforce the environmental dismetabolic aluminum hypothesis of McLaclan (2), i.e., the involvement of abnormal aluminum (III) accumulation in the brain in the etiology of Alzheimer's disease (AD). Another recent review by Deary and Whelley (3) remarkably presents AD as a peculiar syndrome, which(More)
Volatile pollutants produced from several rubber goods manufacturing processes were sampled and analyzed. Samples were collected in the vulcanization areas of a shoe-sole factory, a tire retreading operation, and also in the extrusion areas of the retreading operation and an insulated cable manufacturer. Volatile organics from the vulcanization and(More)
Electrospray ionization mass spectrometry (ESI-MS) has been applied to the study of solution equilibria between Al(III) and the two ligands 4-hydroxy-3-pyridinecarboxylic acid (4H3P) and 3-hydroxy-4-pyridinecarboxylic acid (3H4P). The results compare well with the speciation data obtained from potentiometric, UV-visible spectroscopy, and NMR measurements.(More)