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Recent clinical studies have suggested that the combination of subcutaneous recombinant human interleukin 2 (rIL-2) and interferon alpha (rIFN-alpha) is especially promising in advanced renal cell carcinoma. We assessed the safety, activity and toxicity of home therapy with these two agents in 50 patients. Each treatment cycle consisted of a 2 day pulse(More)
various reasons, as directly and straightforwardly outlined in the discussion of the article. Nevertheless, we are somewhat astonished by the reason for the critical comments by Drs Huland and Heinzer, related for the most part to the fact that they only rely their discussion on non-randomized studies including selected population of patients. In fact, we(More)
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