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A Caucasian female, aged 28 years, presenting with obesity and investigated for primary amenorrhoea, was found to have hydrocephalus due to a stenosis of the foramen of Magendie. Endocrine investigations showed an isolated gonadotrophin deficiency. Complete recovery was obtained by a ventricular-cardiac shunt, which led to the return of menses, a normal(More)
A double blind controlled trial of ornithine alpha-ketoglutarate (OAKG) was carried out on 50 patients admitted to the Royal Free and Royal Northern Hospitals, London, suffering from a recent stroke. Significant improvement was found in patients treated with OAKG when examined on the fifth day of therapy as compared to their control cases. The therapy was(More)