G. Damm

Learn More
Primary human hepatocytes (PHH) are the “gold standard” for in vitro toxicity tests. However, 2D PHH cultures have limitations that are due to a time-dependent dedifferentiation process visible by morphological changes closely connected to a decline of albumin production and CYP450 activity. The 3D in vitro culture corresponds to in vivo-like tissue(More)
– This paper presents an algorithm which prevents a simulation user from choosing a simulation length. This choice is always tricky and often leads to CPU-time waste, not to mention user-time waste. Too often, simulation users forget to compute confidence intervals: they only guess a simulation length and ignore the confidence on the simulation results.(More)
  • 1