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Although a detailed picture is emerging about the nature of the second messengers involved in B cell activation and proliferation, little is yet known about the intracellular events taking place further downstream. The c-myb proto-oncogene, the structurally related B-myb gene, and c-myc probably code for transcription factors, have been demonstrated to be(More)
The authors report tympanometric findings in normal newborns and infants (W-shaped, large smooth-notched curves), comparing them with those obtained in 34 ears of infants aged 5-120 days with middle ear pathology. In most cases a large smooth-notched curve was found, both in cases of serous otitis or purulent otitis. The W-shaped curve was present only in(More)
The long term results are reported of transtympanic drains in 391 ears of 258 children affected by serous otitis; 150 ears have been evaluated at the end of a 3-7-year observation period. (1) A high percentage of ears with major anatomical lesions was found (46.6%), especially in the higher age group (greater than 7 years). (2) Functional hearing results(More)
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