Following the recent analysis of Lucas and Rossi-Hansberg , we study the equilibrium structure of cities. By adopting a different (monetary) specification of commuting costs, we are able to prove the existence of equilibrium in more general situations: non-circular cities, or multi-sectorial production. The main mathematical tool in this paper is the… (More)
In vivo oxidative capacity varies with muscle and training status in young adults energetics Antioxidants and aging: NMR-based evidence of improved skeletal muscle perfusion and Lower energy cost of skeletal muscle contractions in older humans skeletal muscle mitochondria play a role? Impairment of maximal aerobic power with moderate hypoxia in endurance… (More)
We propose a variational model to describe the optimal distributions of residents and services in an urban area. The functional to be minimized involves an overall transportation cost taking into account congestion effects and two aditional terms which penalize concentration of residents and dispersion of services. We study regularity properties of the… (More)
Some cases of parkinsonism without Lewy bodies were detected, although the presence of Lewy bodies is a diagnostic criterion for PD. Thereafter, similar cases were repeatedly encountered by researchers at Juntendo University, Tokyo. Groups in Niigata and Hiroshima also reported cases of parkinsonism without Lewy bodies, which suggests that such cases occur… (More)
Regulation of cell cycle in beta cells is poorly understood, especially in humans. We exploited here the recently described human pancreatic beta cell line EndoC-βH2 to set up experimental systems for cell cycle studies. We derived 2 populations from EndoC-βH2 cells that stably harbor the 2 genes encoding the Fucci fluorescent indicators of cell cycle,… (More)
An exchange economy in which agents have convex incomplete preferences defined by families of concave utility functions is considered. Sufficient conditions for the set of efficient allocations and equi-libria to coincide with the set of efficient allocations and equilibria that result when each agent has a utility in her family are provided. Welfare… (More)
We consider an optimal control problem governed by an ODE with memory playing the role of a control. We show the existence of an optimal solution and derive some necessary optimality conditions. Some examples are then discussed.
This paper studies optimal menus of debt contracts such as secured debentures or bonds, in the presence of diversity of opinions between borrowers and lenders. We first characterize incentive compatible contracts , then prove the existence of optimal debt contracts. Finally, we are able to explicitly characterize such optimal menus within a specific case:… (More)
This paper reports on an 18-month-old achondroplastic child with dilated lateral ventricles. Results of a cisternographic investigation were normal. No shunting procedure was carried out, and subsequent clinical progress was satisfactory. Some patho-physiological aspects of achondroplastic dysgenesis are discussed.