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BACKGROUND Lymphovascular space invasion (LVSI) is one of the most important predictors of nodal involvement and recurrence in early stage endometrial cancer (EC). Despite its demonstrated prognostic value, LVSI has not been incorporated into the European Society of Medical Oncology (ESMO) classification. The aim of this prospective multicentre database(More)
BACKGROUND To compare the accuracy of five major risk stratification systems (RSS) in classifying the risk of recurrence and nodal metastases in early-stage endometrial cancer (EC). METHODS Data of 553 patients with early-stage EC were abstracted from a prospective multicentre database between January 2001 and December 2012. The following RSS were(More)
BACKGROUND To externally validate and assess the robustness of two nomograms to predict the recurrence risk of women with endometrial cancer (EC). METHODS Using an independent, multicentre external patient cohort we assessed the discrimination and calibration of two nomograms--the 3-year isolated loco-regional (ILRR) and distant (DR) recurrence(More)
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